Evidence map›Paper›PMID 35986389›Full record

ArticleAnimal microbiome2022

Succession in the caecal microbiota of developing broilers colonised by extended-spectrum β-lactamase-producing Escherichia coli.

Ingrid Cárdenas-Rey, Teresita D J Bello Gonzalez, Jeanet van der Goot, Daniela Ceccarelli, Gerwin Bouwhuis, Danielle Schillemans, Stephanie D Jurburg, Kees T Veldman, J Arjan G M de Visser, Michael S M Brouwer

Open access · goldAbstract read
In one paragraph

Article in Animal microbiome, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Comparison of IncK-Antibiotics (Basel, Switzerland) · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Ingrid Cárdenas-ReyDepartment of Bacteriology, Host-Pathogen Interactions and Diagnostics Development, Wageningen Bioveterinary Research, Lelystad, The Netherlands.
Teresita D J Bello GonzalezDepartment of Bacteriology, Host-Pathogen Interactions and Diagnostics Development, Wageningen Bioveterinary Research, Lelystad, The Netherlands.
Jeanet van der GootDepartment of Bacteriology, Host-Pathogen Interactions and Diagnostics Development, Wageningen Bioveterinary Research, Lelystad, The Netherlands.
Daniela CeccarelliDepartment of Bacteriology, Host-Pathogen Interactions and Diagnostics Development, Wageningen Bioveterinary Research, Lelystad, The Netherlands.
Gerwin BouwhuisGezondheidscentrum Voor Pluimvee, Emmen, The Netherlands.
Danielle SchillemansDepartment of Bacteriology, Host-Pathogen Interactions and Diagnostics Development, Wageningen Bioveterinary Research, Lelystad, The Netherlands.
Stephanie D JurburgDepartment of Environmental Microbiology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany.
Kees T VeldmanDepartment of Bacteriology, Host-Pathogen Interactions and Diagnostics Development, Wageningen Bioveterinary Research, Lelystad, The Netherlands.
J Arjan G M de VisserLaboratory of Genetics, Wageningen University & Research, Wageningen, The Netherlands.
Michael S M BrouwerDepartment of Bacteriology, Host-Pathogen Interactions and Diagnostics Development, Wageningen Bioveterinary Research, Lelystad, The Netherlands. mike.brouwer@wur.nl.ORCID http://orcid.org/0000-0002-1067-7555
Wageningen University & Research · NLHelmholtz Centre for Environmental Research · DE

Funding

German Research Foundation DFG FZT 118Horizon 2020 773830Netherlands ministry for Agriculture, Nature and Food Quality WOT-01-002-003.11Netherlands ministry for Agriculture, Nature and Food Quality WOT-01-002-016
6 · The paper itself

Abstract

backgroundBroilers are among the most common and dense poultry production systems, where antimicrobials have been used extensively to promote animal health and performance. The continuous usage of antimicrobials has contributed to the appearance of resistant bacteria, such as extended-spectrum β-lactamase-producing Escherichia coli (ESBL-Ec). Here, we studied the ESBL-Ec prevalence and successional dynamics of the caecal microbiota of developing broilers in a commercial flock during their production life cycle (0-35 days). Broilers were categorised as ESBL-Ec colonised (ESBL-Ec

resultsFrom day two, we observed an increasing linear trend in the proportions of ESBL-Ec throughout the broilers' production life cycle, X

conclusionsThis study assessed the role of ESBL-Ec in the successional dynamics of the caecal microbiota in developing broilers and showed that the presence of ESBL-Ec is associated with mild but consistent reductions in alpha diversity and with transient bacterial compositional differences. We also reported the clonal spread of ESBL-Ec and pointed to the farm environment as a likely source for ESBLs.

Indexed as

BroilersESBLEscherichia coliMicrobiota

Identifiers

PMID35986389
PMCPMC9389726
OpenAlexW4292371776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.