ArticleHealth and quality of life outcomes2022
Frailty and its association with health-related quality of life among older cancer patients: an evidence-based study from China.
Article in Health and quality of life outcomes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Relationship between quality of life before treatment and survival in patients with hematological malignancies: A meta-analysis.Fukushima journal of medical science · 2025Pooled it
- Frailty transitions and associated factors in older cancer survivors in the USA: using a multi-state modeling.Journal of cancer survivorship : research and practice · 2026Article
- Article
- The relationship between disability and quality of life among older adults: the roles of sleep, depression, and living arrangements.Frontiers in public health · 2026Article
- Are there different phenotypes of thoracic surgery patients? A latent class analysis of pretreatment patient-reported outcomes.JTCVS open · 2025Article
- Review
- Factors associated with loneliness in middle-aged and older patients with breast cancer.Asia-Pacific journal of oncology nursing · 2024Article
- Frailty in middle-aged and older adult postoperative patients with gynecological malignancies structural equation modeling.Frontiers in public health · 2024Article
- Assessing health-related quality of life among cancer survivors during systemic and radiation therapy in Bangladesh: a cancer-specific exploration.BMC cancer · 2023Article
- Article
- Laparoscopic D2 radical gastrectomy improves postoperative inflammation and gastric function in elderly patients with advanced gastric cancer.American journal of translational research · 2022Article
- Frailty among inpatients with Schizophrenia: Status, influencing factors, and their correlation with quality of life.Frontiers in psychiatry · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundThere is limited information about the population characteristics and adverse health outcomes of older cancer patients in China. This study aimed to describe the prevalence of frailty and examine the association between frailty and health-related quality of life (HRQoL) among older cancer patients.
methodsThis was a cross-sectional study involving older patients diagnosed with cancer in two tertiary hospitals in Shandong Province, China. Frailty was assessed using Geriatric 8 (G-8). HRQoL was measured using the five-level EuroQol-5-dimension (EQ-5D-5L) questionnaire. The Tobit regression model and logistic regression model was used to identify the relationship between frailty and HRQoL.
resultsOf the 229 older patients, 175 (76.4%) were frail. Frail patients had lower EQ-5D-5L utility scores than those who were non-frail (0.830 vs. 0.889; P = 0.004). After adjustments for sociodemographic and cancer-related variables, frailty was statistically associated with worse health-related quality of life (OR = 6.024; P = 0.001).
conclusionFrailty was associated with deteriorated HRQoL in older patients with cancer. Early frailty screening and preventive interventions are essential for improving quality of life through decision-making or pretreatment optimization in geriatric oncology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.