Evidence map›Paper›PMID 35985738›Full record

ArticleBMJ case reports2022

Hypercalcaemia as the initial presentation of Graves' disease.

Kirandeep Kaur, Nisha Batra, Kavita Kadian, Kalyani Sridharan

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kirandeep KaurEndocrinology, All India Institute of Medical Sciences - Rishikesh, Rishikesh, Uttarakhand, India.
Nisha BatraEndocrinology, All India Institute of Medical Sciences - Rishikesh, Rishikesh, Uttarakhand, India.
Kavita KadianEndocrinology, All India Institute of Medical Sciences - Rishikesh, Rishikesh, Uttarakhand, India.
Kalyani SridharanEndocrinology, All India Institute of Medical Sciences - Rishikesh, Rishikesh, Uttarakhand, India sridharan.kalyani22@gmail.com.ORCID http://orcid.org/0000-0002-5867-5073

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypercalcaemia in patients with hyperthyroidism is usually asymptomatic. It occurs due to increased bone turnover and demineralisation. There are only a few case reports where symptomatic hypercalcaemia was the presenting complaint of hyperthyroidism. An Asian man in his 40s presented to us with intractable vomiting for the last 6 months which was not controlled despite multiple antiemetic medications. On routine biochemistry performed at our institute, he was found to have hypercalcaemia and concomitant hyperthyroidism. Classical symptoms suggestive of hyperthyroidism were not present in our patient thus delaying the diagnosis. His symptoms resolved after the correction of hypercalcaemia. Hypercalcaemia did not recur after achieving an euthyroid status on treatment with carbimazole. Other common and more sinister causes for hypercalcaemia like malignancy were ruled out. This case highlights that symptomatic hypercalcaemia could be the initial presentation of hyperthyroidism and amelioration of hyperthyroidism corrects the hypercalcaemia.

Indexed as

Graves DiseaseHypercalcemiaHyperthyroidismAntithyroid AgentsCarbimazoleHumansMaleAntithyroid AgentsCarbimazoleGeneral practice / family medicineThyroid disease

Identifiers

PMID35985738
PMCPMC9396191

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.