Evidence map›Paper›PMID 35985031›Full record

ArticleBiochemistry2022

Structural Basis of Stereospecific Vanadium-Dependent Haloperoxidase Family Enzymes in Napyradiomycin Biosynthesis.

Percival Yang-Ting Chen, Sanjoy Adak, Jonathan R Chekan, David K Liscombe, Akimasa Miyanaga, Peter Bernhardt, Stefan Diethelm, Elisha N Fielding, Jonathan H George, Zachary D Miles and 5 more

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  9. Peptide halogenation biochemistry: interfacing pharmaceutical deliverables with chemical innovation.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Percival Yang-Ting ChenCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, United States.ORCID 0000-0001-7362-9801
Sanjoy AdakCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, United States.
Jonathan R ChekanCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, United States.ORCID 0000-0003-4651-0594
David K LiscombeJack H. Skirball Center for Chemical Biology and Proteomics, The Salk Institute for Biological Studies, La Jolla, California 92037, United States.
Akimasa MiyanagaCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, United States.ORCID 0000-0003-2219-6051
Peter BernhardtCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, United States.
Stefan DiethelmCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, United States.
Elisha N FieldingCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, United States.
Jonathan H GeorgeDepartment of Chemistry, University of Adelaide, Adelaide, South Australia 5005, Australia.ORCID 0000-0002-7330-2160
Zachary D MilesCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, United States.
Lauren A M MurrayDepartment of Chemistry, University of Adelaide, Adelaide, South Australia 5005, Australia.
Taylor S SteeleCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, United States.
Jaclyn M WinterCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, United States.ORCID 0000-0001-6273-5377
Joseph P NoelJack H. Skirball Center for Chemical Biology and Proteomics, The Salk Institute for Biological Studies, La Jolla, California 92037, United States.ORCID 0000-0002-1277-0331
Bradley S MooreCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093, United States.ORCID 0000-0002-4652-1253
Scripps Institution of Oceanography · USSalk Institute for Biological Studies · USThe University of Adelaide · AU

Funding

User Training and OutreachP30GM124169 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI PAUL David ADAMS, Gregory L Hura · 2017 to 2026
$28.6M
ENGINEERING DIVERSITY WITH ENTEROCIN BIOSYNTHESIS GENER01AI047818 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MOORE, BRADLEY S · 2000 to 2022
$5.2M
Acquisition of a High Resolution TOF Mass SpectrometerS10RR025636 · NCRR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MOLINSKI, TADEUSZ F · 2010 to 2010
$305k
Next-generation sequencing as a platform for actinomycete natural product discoveF32GM096711 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BERNHARDT, PETER · 2011 to 2012
$57k
Howard Hughes Medical InstituteNCRR NIH HHS S10 RR025636NIAID NIH HHS R01 AI047818NIGMS NIH HHS F32 GM096711NIGMS NIH HHS P30 GM124169
6 · The paper itself

Abstract

Vanadium-dependent haloperoxidases (VHPOs) from

Indexed as

StreptomycesVanadiumAnti-Bacterial AgentsCatalysisIsomerasesAnti-Bacterial AgentsIsomerasesVanadium

Identifiers

PMID35985031
PMCPMC10978243
OpenAlexW4292358546

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.