ArticlePlant biotechnology journal2022
The salivary effector protein Sg2204 in the greenbug Schizaphis graminum suppresses wheat defence and is essential for enabling aphid feeding on host plants.
Article in Plant biotechnology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 59 citations in OpenAlex.
- Gb3 encodes a unique kinase fusion protein conferring greenbug resistance in wheat.Nature genetics · 2026Article
- The salivary protein NlG8 from Nilaparvata lugens induces both direct and indirect resistance in host rice plants.The New phytologist · 2026Article
- Molecular and transcriptional regulation of plant defense responses to aphid infestation.Stress biology · 2026Review
- Molecular interface of plant-insect warfare: functions and applications of salivary effectors in piercing-sucking pests.Pest management science · 2026Review
- Plant-Aphid Interactions in Cereal Crops: Wheat Plant Defense and Aphid Saliva-Mediated Coevolutionary Arms Race.Insects · 2026Review
- Host-Induced Gene Silencing ofCurrent issues in molecular biology · 2026Article
- Transcriptome analysis and characterization of cathepsin B-like protein inMolecular breeding : new strategies in plant improvement · 2026Article
- The Mitochondrial Protein RESISTANCE to APHIDS 9 Interacts with S40 to Resist Aphid Infestation by Modulating Reactive Oxygen Species Homeostasis in Maize (Zea mays).Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Transcriptomic analysis reveals candidate molecular pathways involved in pea (Pisum sativum L.) resistance to pea aphid (Acyrthosiphon pisum Harris) biotypes.BMC genomics · 2025Article
- HrpW Modulates Paracidovorax citrulli Virulence and Plant Immunity via ClRAR1 Interaction in Watermelon.Molecular plant pathology · 2025Article
- Loss-of-function of LIGULELESS1 activates the jasmonate pathway and promotes maize resistance to corn leaf aphids.Plant biotechnology journal · 2024Article
- Molecular Interactions Between Plants and Aphids: Recent Advances and Future Perspectives.Insects · 2024Review
- Article
- Cotton Bollworm (H. armigera) Effector PPI5 Targets FKBP17-2 to Inhibit ER Immunity and JA/SA Responses, Enhancing Insect Feeding.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Article
- Salivary Protein Cyclin-Dependent Kinase-like from Grain AphidInternational journal of molecular sciences · 2024Article
- Untapped Sources of Dual Resistance to Hessian Fly and Greenbug in Synthetic Hexaploid Wheats.Plants (Basel, Switzerland) · 2023Article
- A Method for Identification of Biotype-Specific Salivary Effector Candidates of Aphid.Insects · 2023Article
- Transcriptomic and Proteomic Analyses ofBiology · 2023Article
- Two salivary proteins Sm10 and SmC002 from grain aphidFrontiers in plant science · 2023Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aphids secrete diverse repertoires of salivary effectors into host plant cells to promote infestation by modulating plant defence. The greenbug Schizaphis graminum is an important cereal aphid worldwide. However, the secreted effectors of S. graminum are still uncharacterized. Here, 76 salivary proteins were identified from the watery saliva of S. graminum using transcriptome and proteome analyses. Among them, a putative salivary effector Sg2204 was significantly up-regulated during aphid feeding stages, and transient overexpression of Sg2204 in Nicotiana benthamiana inhibited cell death induced by BAX or INF1. Delivering Sg2204 into wheat via the type III secretion system of Pseudomonas fluorescens EtAnH suppressed pattern-triggered immunity (PTI)-associated callose deposition. The transcript levels of jasmonic acid (JA)- and salicylic acid (SA)-associated defence genes of wheat were significantly down-regulated, and the contents of both JA and SA were also significantly decreased after delivery of Sg2204 into wheat leaves. Additionally, feeding on wheat expressing Sg2204 significantly increased the weight and fecundity of S. graminum and promoted aphid phloem feeding. Sg2204 was efficiently silenced via spray-based application of the nanocarrier-mediated transdermal dsRNA delivery system. Moreover, Sg2204-silenced aphids induced a stronger wheat defence response and resulted in negative impacts on aphid feeding behaviour, survival and fecundity. Silencing of Sg2204 homologues from four aphid species using nanocarrier-delivered dsRNA also significantly reduced aphid performance on host plants. Thus, our study characterized the salivary effector Sg2204 of S. graminum involved in promoting host susceptibility by suppressing wheat defence, which can also be regarded as a promising RNAi target for aphid control.
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