Evidence map›Paper›PMID 35984784›Full record

ArticlePloS one2022

Characterization of GafChromic EBT2 film dose measurements using a tissue-equivalent water phantom for a Theratron® Equinox Cobalt-60 teletherapy machine.

Daniel Akwei Addo, Elsie Effah Kaufmann, Samuel Nii Tagoe, Augustine Kwame Kyere

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Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Daniel Akwei AddoDepartment of Computer Engineering, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.ORCID 0000-0002-8747-4289
Elsie Effah KaufmannDepartment of Biomedical Engineering, School of Engineering Sciences, University of Ghana, Legon, Accra, Ghana.ORCID 0000-0001-7675-4333
Samuel Nii TagoeNational Radiotherapy Oncology and Nuclear Medicine Centre, Korle-Bu, Accra, Ghana.
Augustine Kwame KyereMedical Physics Department, Graduate School of Nuclear and Allied Sciences, University of Ghana, Atomic, Accra, Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn vivo dosimetry is a quality assurance tool that provides post-treatment measurement of the absorbed dose as delivered to the patient. This dosimetry compares the prescribed and measured dose delivered to the target volume. In this study, a tissue-equivalent water phantom provided the simulation of the human environment. The skin and entrance doses were measured using GafChromic EBT2 film for a Theratron® Equinox Cobalt-60 teletherapy machine.

methodsWe examined the behaviors of unencapsulated films and custom-made film encapsulation. Films were cut to 1 cm × 1 cm, calibrated, and used to assess skin dose depositions and entrance dose. We examined the response of the film for variations in field size, source to skin distance (SSD), gantry angle and wedge angle.

resultsThe estimated uncertainty in EBT2 film for absorbed dose measurement in phantom was ±1.72%. Comparison of the measurements of the two film configurations for the various irradiation parameters were field size (p = 0.0193, α = 0.05, n = 11), gantry angle (p = 0.0018, α = 0.05, n = 24), SSD (p = 0.1802, α = 0.05, n = 11) and wedge angle (p = 0.6834, α = 0.05, n = 4). For a prescribed dose of 200 cGy and at reference conditions (open field 10 cm x 10 cm, SSD = 100 cm, and gantry angle = 0º), the measured skin dose using the encapsulation material was 70% while that measured with the unencapsulated film was 24%. At reference irradiation conditions, the measured skin dose using the unencapsulated film was higher for open field configurations (24%) than wedged field configurations (19%). Estimation of the entrance dose using the unencapsulated film was within 3% of the prescribed dose.

conclusionsGafChromic EBT2 film measurements were significantly affected at larger field sizes and gantry angles. Furthermore, we determined a high accuracy in entrance dose estimations using the film.

Indexed as

Film DosimetryWaterCobalt RadioisotopesHumansPhantoms, ImagingCobalt-60Cobalt RadioisotopesWater

Identifiers

PMID35984784
PMCPMC9390906

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.