ArticleThe American journal of sports medicine2022
Predicting ACL Injury Using Machine Learning on Data From an Extensive Screening Test Battery of 880 Female Elite Athletes.
Article in The American journal of sports medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 5 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- The application of machine learning in the prediction of sports injuries: systematic review and meta-analysis.Scientific reports · 2026Pooled it
- Artificial intelligence in ACL injury prediction and prevention: a systematic review.Journal of orthopaedic surgery and research · 2026Pooled it
- Machine Learning Applications in Non-Contact Lower Limb Sports Injury Prediction: A Systematic Review.Journal of sports science & medicine · 2026Pooled it
- Influence of Neuromuscular Training Interventions on Jump-Landing Biomechanics and Implications for ACL Injuries in Youth Females: A Systematic Review and Meta-analysis.Sports medicine (Auckland, N.Z.) · 2025Pooled it
- Injury Prevention Programmes Fail to Change Most Lower Limb Kinematics and Kinetics in Female Team Field and Court Sports: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.Sports medicine (Auckland, N.Z.) · 2024Pooled it
- Can Field-Based Screening Predict ACL Injury Risk in Women Footballers? External Validation of a Prediction Model.Sports health · 2026Article
- Artificial intelligence and machine learning in sports medicine: mapping clinical tasks and assessing clinical maturity - a scoping review.BMC medical informatics and decision making · 2026Article
- Athletes' performance and injury management in sports training using association rules and data mining techniques.Scientific reports · 2026Article
- Artificial Intelligence in Sports Medicine: A Decision-Centered Framework for the Future Sports Physician.Diagnostics (Basel, Switzerland) · 2026Review
- Utilization of machine learning to identify lower extremity biomechanical predictors of rupture in a validated cadaveric model of ACL injury.Scientific reports · 2026Article
- Can We Predict Adductor Strain? A Predictive Analysis of a Major League Soccer (MLS) Cohort Spanning from 2019 to 2022.Journal of functional morphology and kinesiology · 2026Article
- Development and validation of a machine learning model for non-contact injury prediction based on lower limb strength asymmetry in professional football.Scientific reports · 2026Article
- Markerless 3D motion capture in return to sport decision making for ACL injured high level athletes: a narrative review with proposed clinical implementation pathway.Annals of joint · 2026Review
- Machine Learning-Based Prediction of Muscle Injury Risk in Professional Football: A Four-Year Longitudinal Study.Journal of clinical medicine · 2025Article
- A practical guide to the implementation of artificial intelligence in orthopaedic research-Part 3: How orthopaedic research benefits from the implementation of artificial intelligence.Journal of experimental orthopaedics · 2025Review
- Machine learning approaches to injury risk prediction in sport: a scoping review with evidence synthesis.British journal of sports medicine · 2025Article
- Article
- Anatomic Risk Factors for Initial and Secondary Noncontact Anterior Cruciate Ligament Injury: A Prospective Cohort Study in 880 Female Elite Handball and Soccer Players.The American journal of sports medicine · 2025Article
- A Critical Review of Trunk and Hip Exercise Prescription: Applying Evidence for a Modern Approach.International journal of sports physical therapy · 2025Article
- Predicting special forces dropout via explainable machine learning.European journal of sport science · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInjury risk prediction is an emerging field in which more research is needed to recognize the best practices for accurate injury risk assessment. Important issues related to predictive machine learning need to be considered, for example, to avoid overinterpreting the observed prediction performance. PURPOSE: To carefully investigate the predictive potential of multiple predictive machine learning methods on a large set of risk factor data for anterior cruciate ligament (ACL) injury; the proposed approach takes into account the effect of chance and random variations in prediction performance. STUDY
designCase-control study; Level of evidence, 3.
methodsThe authors used 3-dimensional motion analysis and physical data collected from 791 female elite handball and soccer players. Four common classifiers were used to predict ACL injuries (n = 60). Area under the receiver operating characteristic curve (AUC-ROC) averaged across 100 cross-validation runs (mean AUC-ROC) was used as a performance metric. Results were confirmed with repeated permutation tests (paired Wilcoxon signed-rank-test;
resultsFor the best classifier (linear support vector machine), the mean AUC-ROC was 0.63. Regardless of the classifier, the results were significantly better than chance, confirming the predictive ability of the data and methods used. AUC-ROC values varied substantially across repetitions and methods (0.51-0.69). Class imbalance handling did not improve the results.
conclusionThe authors' approach and data showed statistically significant predictive ability, indicating that there exists information in this prospective data set that may be valuable for understanding injury causation. However, the predictive ability remained low from the perspective of clinical assessment, suggesting that included variables cannot be used for ACL prediction in practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.