Evidence map›Paper›PMID 35984745›Full record

ArticleGut microbes

Dual RNA-seq reveals a type 6 secretion system-dependent blockage of TNF-α signaling and BicA as a

Javier I Sanchez-Villamil, Daniel Tapia, Nittaya Khakhum, Steven G Widen, Alfredo G Torres

Open access · goldAbstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Opsonization Improves Dual Proteomic Analysis ofJournal of proteome research · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Dual RNA sequencing ofmSystems · 2024
    Article
  6. Burkholderia pseudomallei and melioidosis.Nature reviews. Microbiology · 2024
    Review
  7. Article
  8. mSphere · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Javier I Sanchez-VillamilDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.ORCID 0000-0003-4928-5994
Daniel TapiaDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.ORCID 0000-0001-9652-2572
Nittaya KhakhumDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.
Steven G WidenDepartment of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, USA.ORCID 0000-0002-6512-363X
Alfredo G TorresDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.ORCID 0000-0001-6450-0643
The University of Texas Medical Branch at Galveston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melioidosis is a disease caused by the Gram-negative bacillus

Indexed as

Burkholderia pseudomalleiGastrointestinal MicrobiomeMelioidosisType VI Secretion SystemsVirulence FactorsAnimalsBacterial ProteinsMiceMolecular ChaperonesRNA-SeqSoilTumor Necrosis Factor-alphaWaterBacterial ProteinsMolecular ChaperonesSoilTumor Necrosis Factor-alphaType VI Secretion SystemsVirulence FactorsWaterBurkholderia pseudomalleigastrointestinal infectionmelioidosistype 6 secretion system

Identifiers

PMID35984745
PMCPMC9397134
OpenAlexW4292681834

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.