Evidence map›Paper›PMID 35984599›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2022

Genomic characterization of Salmonella enterica serovar Choleraesuis from Brazil reveals a swine gallbladder isolate harboring colistin resistance gene mcr-1.1.

Felipe Pinheiro Vilela, Dália Dos Prazeres Rodrigues, Joseane Cristina Ferreira, Ana Lúcia da Costa Darini, Marc William Allard, Juliana Pfrimer Falcão

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. One Health at Risk: Plasmid-Mediated Spread ofAntibiotics (Basel, Switzerland) · 2025
    Review
  3. Review
  4. Review
  5. Hybrid Genomic Analysis ofMicroorganisms · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Felipe Pinheiro VilelaDepartamento de Análises Clínicas, Toxicológicas E Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto - USP, Av. do Café, s/n, Ribeirão Preto, SP, 14040-903, Brazil.ORCID http://orcid.org/0000-0002-7506-6181
Dália Dos Prazeres RodriguesFundação Oswaldo Cruz - FIOCRUZ, Pavilhão Rocha Lima, Av. Brasil, 4365, Rio de Janeiro, RJ, 21040-900, Brazil.
Joseane Cristina FerreiraDepartamento de Análises Clínicas, Toxicológicas E Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto - USP, Av. do Café, s/n, Ribeirão Preto, SP, 14040-903, Brazil.
Ana Lúcia da Costa DariniDepartamento de Análises Clínicas, Toxicológicas E Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto - USP, Av. do Café, s/n, Ribeirão Preto, SP, 14040-903, Brazil.
Marc William AllardDivision of Microbiology, Office of Regulatory Science, Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, MD, USA. Marc.Allard@fda.hhs.gov.
Juliana Pfrimer FalcãoDepartamento de Análises Clínicas, Toxicológicas E Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto - USP, Av. do Café, s/n, Ribeirão Preto, SP, 14040-903, Brazil. jufalcao@fcfrp.usp.br.ORCID http://orcid.org/0000-0002-1459-9355
SUPERA Park of Innovation and Technology of Ribeirão Preto · BRCenter for Food Safety and Applied Nutrition · USFundação Oswaldo Cruz · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 141017/2021-0Conselho Nacional de Desenvolvimento Científico e Tecnológico 304399/2018-3Conselho Nacional de Desenvolvimento Científico e Tecnológico 304803/2021-9Fundação de Amparo à Pesquisa do Estado de São Paulo 2019/06947-6Fundação de Amparo à Pesquisa do Estado de São Paulo 2019/19338-8
6 · The paper itself

Abstract

Salmonella enterica serovar Choleraesuis (S. Choleraesuis) is a swine-adapted serovar associated to invasive infections in humans. In Brazil, data of strains of this serovar are scarce. In the present study, six S. Choleraesuis strains of animal (n = 5) and human (n = 1) origin from Brazil were screened for phenotypic antimicrobial resistance using disk-diffusion assay and using whole-genome sequencing data to search for antimicrobial resistance genes, plasmids, prophages, and Salmonella pathogenicity islands (SPIs). Its genetic relatedness was evaluated by MLST and SNP analysis. A single isolate from swine gallbladder harbored the colistin resistance gene mcr-1.1 into a IncX4 plasmid. In the six strains analyzed, resistance was found to tetracycline, nalidixic acid, ciprofloxacin, ampicillin, piperacillin, streptomycin, cefazoline, gentamycin, sulfamethoxazole-trimethoprim, and choloramphenicol, along with resistance genes aac(6')-Iaa, aac(3)-IV, aph(3'')-Ib, aph(6)-Id, aph(4)-Ia, aadA1, aph(3')-IIa, bla

Indexed as

ColistinSalmonella entericaAnimalsAnti-Bacterial AgentsBrazilDrug Resistance, Multiple, BacterialGallbladderGenomicsMicrobial Sensitivity TestsMultilocus Sequence TypingPlasmidsSalmonellaSerogroupSwineAnti-Bacterial AgentsColistinColistin resistanceMultidrug resistanceSalmonella CholeraesuisSwineWhole-genome sequencing

Identifiers

PMID35984599
PMCPMC9679059
OpenAlexW4292493773

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.