Evidence map›Paper›PMID 35984531›Full record

ArticleEJNMMI physics2022

Positron range in combination with point-spread-function correction: an evaluation of different implementations for [124I]-PET imaging.

Hunor Kertész, Maurizio Conti, Vladimir Panin, Jorge Cabello, Deepak Bharkhada, Thomas Beyer, Laszlo Papp, Walter Jentzen, Jacobo Cal-Gonzalez, Joaquín L Herraiz and 2 more

Open access · goldAbstract read
In one paragraph

Article in EJNMMI physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Multiplexed imaging of radionuclides.Nature biomedical engineering · 2025
    Review
  4. Positron Range Correction Helps Enhance the Image Quality of CardiacJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 4 countries.

Hunor KertészQIMP Team, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria. hunor.kertesz@meduniwien.ac.at.ORCID http://orcid.org/0000-0002-4626-930X
Maurizio ContiSiemens Medical Solutions USA, Inc., Knoxville, TN, USA.
Vladimir PaninSiemens Medical Solutions USA, Inc., Knoxville, TN, USA.
Jorge CabelloSiemens Medical Solutions USA, Inc., Knoxville, TN, USA.
Deepak BharkhadaSiemens Medical Solutions USA, Inc., Knoxville, TN, USA.
Thomas BeyerQIMP Team, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Laszlo PappQIMP Team, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Walter JentzenClinic for Nuclear Medicine, University Hospital Essen, Essen, Germany.
Jacobo Cal-GonzalezQIMP Team, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Joaquín L HerraizNuclear Physics Group and IPARCOS, Faculty of Physical Sciences, University Complutense of Madrid, Madrid, Spain.
Alejandro López-MontesNuclear Physics Group and IPARCOS, Faculty of Physical Sciences, University Complutense of Madrid, Madrid, Spain.
Ivo RauschQIMP Team, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Medical University of Vienna · ATSiemens (United States) · USUniversidad Complutense de Madrid · ESEssen University Hospital · DE

Funding

Austrian Science Fund I3451-N32
6 · The paper itself

Abstract

aimTo evaluate the effect of combining positron range correction (PRC) with point-spread-function (PSF) correction and to compare different methods of implementation into iterative image reconstruction for MATERIALS AND

methodsUniform PR blurring kernels of

resultsContrast recovery improved by 2-10% and 4-37% with OSEM+PRC simplified and OSEM+PRC, respectively, depending on the sphere size of the NEMA IQ phantom. Including PSF in the reconstructions further improved contrast by 4-19% and 3-16% with the PSF+PRC simplified and PSF+PRC, respectively. The benefit of PRC was more pronounced within low-density material. OSEM-PRC and OSEM-PSF as well as OSEM-PSF+PRC in its full- and simplified implementation showed comparable noise and convergence. OSEM-PRC simplified showed comparably faster convergence but at the cost of increased image noise.

conclusionsThe combination of the PSF and PRC leads to increased contrast recovery with reduced image noise compared to stand-alone PSF or PRC reconstruction. For OSEM-PRC reconstructions, a full implementation in the reconstruction is necessary to handle image noise. For the combination of PRC with PSF, a simplified PRC implementation can be used to reduce reconstruction times.

Indexed as

Image reconstructionPETPositron range correctionPRC

Identifiers

PMID35984531
PMCPMC9391565
OpenAlexW4292371798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.