Evidence map›Paper›PMID 35984318›Full record

ArticleInternational journal of epidemiology2023

Quantifying cause-related mortality in Australia, incorporating multiple causes: observed patterns, trends and practical considerations.

Karen Bishop, Margarita Moreno-Betancur, Saliu Balogun, James Eynstone-Hinkins, Lauren Moran, Chalapati Rao, Emily Banks, Rosemary J Korda, Michelle Gourley, Grace Joshy

Open access · hybridAbstract read
In one paragraph

Article in International journal of epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Reclassification and weighting of multiple causes of death: US death certificates 2003-2023.Proceedings of the National Academy of Sciences of the United States of America · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Karen BishopNational Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT, Australia.ORCID 0000-0003-1758-9598
Margarita Moreno-BetancurClinical Epidemiology and Biostatistics Unit, Murdoch Children's Research Institute, Melbourne, VIC, Australia.ORCID 0000-0002-8818-3125
Saliu BalogunNational Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT, Australia.
James Eynstone-HinkinsHealth and Vital Statistics Section, Australian Bureau of Statistics, Canberra, ACT, Australia.
Lauren MoranHealth and Vital Statistics Section, Australian Bureau of Statistics, Canberra, ACT, Australia.
Chalapati RaoNational Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT, Australia.ORCID 0000-0002-9554-0581
Emily BanksNational Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT, Australia.ORCID 0000-0002-4617-1302
Rosemary J KordaNational Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT, Australia.
Michelle GourleyPopulation Health Group, Australian Institute of Health and Welfare, Canberra, ACT, Australia.
Grace JoshyNational Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT, Australia.
Australian National University · AUAustralian Bureau of Statistics · AUAustralian Institute of Health and Welfare · AUThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMortality statistics using a single underlying cause of death (UC) are key health indicators. Rising multimorbidity and chronic disease mean that deaths increasingly involve multiple conditions. However, additional causes reported on death certificates are rarely integrated into mortality indicators, partly due to complexities in data and methods. This study aimed to assess trends and patterns in cause-related mortality in Australia, integrating multiple causes (MC) of death.

methodsDeaths (n = 1 773 399) in Australia (2006-17) were mapped to 136 ICD-10-based groups and MC indicators applied. Age-standardized cause-related rates (deaths/100 000) based on the UC (ASRUC) were compared with rates based on any mention of the cause (ASRAM) using rate ratios (RR = ASRAM/ASRUC) and to rates based on weighting multiple contributing causes (ASRW).

resultsDeaths involved on average 3.4 causes in 2017; the percentage with >4 causes increased from 20.9 (2006) to 24.4 (2017). Ischaemic heart disease (ASRUC = 73.3, ASRAM = 135.8, ASRW = 63.5), dementia (ASRUC = 51.1, ASRAM = 98.1, ASRW = 52.1) and cerebrovascular diseases (ASRUC = 39.9, ASRAM = 76.7, ASRW = 33.5) ranked as leading causes by all methods. Causes with high RR included hypertension (ASRUC = 2.2, RR = 35.5), atrial fibrillation (ASRUC = 8.0, RR = 6.5) and diabetes (ASRUC = 18.5, RR = 3.5); the corresponding ASRW were 12.5, 12.6 and 24.0, respectively. Renal failure, atrial fibrillation and hypertension ranked among the 10 leading causes by ASRAM and ASRW but not by ASRUC. Practical considerations in working with MC data are discussed.

conclusionsDespite the similarities in leading causes under the three methods, with integration of MC several preventable diseases emerged as leading causes. MC analyses offer a richer additional perspective for population health monitoring and policy development.

Indexed as

Atrial FibrillationDiabetes MellitusHypertensionCausalityCause of DeathHumansMortalitychronic diseasescomorbidityMortalitymultiple causes of deathpopulation healthrisk factors

Identifiers

PMID35984318
PMCPMC9908048
OpenAlexW4294349345

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.