Evidence map›Paper›PMID 35984088›Full record

ArticleJournal of the American Geriatrics Society2022

Psychotropic medication prescribing in assisted living and nursing home residents with dementia after the National Partnership.

Antoinette B Coe, Tingting Zhang, Andrew R Zullo, Lauren B Gerlach, Kali S Thomas, Lori A Daiello, Hiren Varma, Derrick Lo, Richa Joshi, Theresa I Shireman and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Antidepressant Use Among US Nursing Home Residents With Dementia.Journal of the American Geriatrics Society · 2026
    Article
  4. Impact of national partnership to improve dementia care on antipsychotic use duration for dementia residents in nursing homes.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Observational
  13. State Variation in Antipsychotic Use Among Assisted Living Residents With Dementia.Journal of the American Medical Directors Association · 2023
    Observational
  14. Article
  15. Article
  16. Negative Lifestyle Factors Specific to Aging Persons Living with HIV and Multimorbidity.Journal of the International Association of Providers of AIDS Care
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Antoinette B CoeDepartment of Clinical Pharmacy, College of Pharmacy, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-5723-0443
Tingting ZhangCenter for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, Rhode Island, USA.
Andrew R ZulloCenter for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, Rhode Island, USA.ORCID 0000-0003-1673-4570
Lauren B GerlachInstitute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0003-1943-0150
Kali S ThomasCenter for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, Rhode Island, USA.
Lori A DaielloCenter for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, Rhode Island, USA.
Hiren VarmaCenter for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, Rhode Island, USA.
Derrick LoCenter for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, Rhode Island, USA.
Richa JoshiCenter for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, Rhode Island, USA.
Theresa I ShiremanCenter for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, Rhode Island, USA.
Julie P W BynumInstitute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, Michigan, USA.
Brown University · USUniversity of Michigan · US

Funding

VARIATIONS IN LIFE'S FINAL CHAPTERP01AG027296 · NIA · BROWN UNIVERSITY · PI AMAL N. TRIVEDI · 2007 to 2026
$38.9M
Medications and the Risk of Motor Vehicle Crashes in Older AdultsR01AG065722 · NIA · BROWN UNIVERSITY · PI ZULLO, ANDREW REIS · 2020 to 2023
$2.1M
Improving Medication Use and Outcomes in Older Adults with Dementia after Hospitalization: Effectiveness of Medicare ProgramsK08AG071856 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COE, ANTOINETTE BARTOLOTTA · 2021 to 2024
$620k
NIA NIH HHS K08 AG071856NIA NIH HHS P01 AG027296NIA NIH HHS R01 AG065722
6 · The paper itself

Abstract

backgroundThe Centers for Medicare & Medicaid Services implemented the National Partnership to Improve Dementia Care in Nursing Homes (the Partnership) to decrease antipsychotic use and improve care for nursing home (NH) residents with dementia. We determined whether the extent of antipsychotic and other psychotropic medication prescribing in AL residents with dementia mirrored that of long-stay NH (LSNH) residents after the Partnership.

methodsUsing a 20% sample of fee-for-service Medicare beneficiaries with Part D, we conducted a retrospective cohort study including AL and LSNH residents with dementia. The monthly prevalence of psychotropic medication prescribing (antipsychotics, antidepressants, anxiolytics/sedative-hypnotics, anticonvulsants/mood stabilizers, benzodiazepines, and antidementia medications) was examined. We used an interrupted time-series analysis to compare medication prescribing before (July 1, 2010-March 31, 2012) and after (April 1, 2012-December 31, 2017) the Partnership in both settings.

resultsWe identified 107,931 beneficiaries with ≥1 month as an AL resident and 323,766 beneficiaries with ≥1 month as a LSNH resident with dementia, including 1,923,867 person-months and 4,984,405 person-months, respectively. Antipsychotic prescribing declined over the study period in both settings. After the launch of the Partnership, the rate of decline in antipsychotic prescribing slowed in AL residents with dementia (slope change = 0.03 [95% CLs: 0.02, 0.04]) while the rate of decline in antipsychotic prescribing increased in LSNH residents with dementia (slope change = -0.12 [95% CLs: -0.16, -0.08]). Antidepressants were the most prevalent medication prescribed, anticonvulsant/mood stabilizer prescribing increased, and anxiolytic/sedative-hypnotic and antidementia medication prescribing declined.

conclusionsThe federal Partnership to reduce antipsychotic prescribing in NH residents did not appear to affect antipsychotic prescribing in AL residents with dementia. Given the increase in the prescribing of mood stabilizers/anticonvulsants that occurred after the launch of the Partnership, monitoring may be warranted for all psychotropic medications in AL and NH settings.

Indexed as

Antipsychotic AgentsDementiaAgedAnticonvulsantsAntidepressive AgentsHumansHypnotics and SedativesMedicareNursing HomesPsychotropic DrugsRetrospective StudiesUnited StatesAnticonvulsantsAntidepressive AgentsAntipsychotic AgentsHypnotics and SedativesPsychotropic DrugsAlzheimer diseaseassisted living facilitiesdementianursing homespsychotropic drugs

Identifiers

PMID35984088
PMCPMC9771901
OpenAlexW4292371710

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.