ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2023
Cardiac Complications of Human Babesiosis.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Cardiovascular Complications of Anaplasmosis: A Case of Acute Pulmonary Embolism and Literature Review.Infectious disease reports · 2026Article
- Epidemiological, Clinical and Analytical Features in Lyme Borreliosis Patients Seropositive forMicroorganisms · 2025Article
- Article
- From Tick Bite to Broken Heart: A Case of Stress Cardiomyopathy Induced by Severe Babesiosis.Cureus · 2025Article
- Severe Anaplasmosis with Multi-Organ Failure in a Patient with Splenectomy: A Case Report.Infectious disease reports · 2025Article
- Prevalence ofMicroorganisms · 2024Article
- Article
- Case Report: Diagnosis of Hemolytic Anemia from Babesia and Secondary Multi-Pathogen Pneumonia Using a Metagenomic Next-Generation Sequencing Approach.Infection and drug resistance · 2024Article
- Comparing the Epidemiology and Health Burden of Lyme Disease and Babesiosis Hospitalizations in the United States.Open forum infectious diseases · 2022Article
- A lethal combination: fulminant liver failure due toTherapeutic advances in infectious diseaseArticle
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4 authors.
Funding
Abstract
backgroundHuman babesiosis is a worldwide emerging tick-borne disease caused by intraerythrocytic protozoa. Most patients experience mild to moderate illness, but life-threatening complications can occur. Although cardiac complications are common, the full spectrum of cardiac disease and the frequency, risk factors, and outcomes in patients experiencing cardiac complications are unclear. Accordingly, we carried out a record review of cardiac complications among patients with babesiosis admitted to Yale-New Haven Hospital over the last decade to better characterize cardiac complications of babesiosis.
methodsWe reviewed the medical records of all adult patients with babesiosis admitted to Yale-New Haven Hospital from January 2011 to October 2021, confirmed by identification of Babesia parasites on thin blood smear and/or by polymerase chain reaction. The presence of Lyme disease and other tick-borne disease coinfections were recorded.
resultsOf 163 enrolled patients, 32 (19.6%) had ≥1 cardiac complication during hospitalization. The most common cardiac complications were atrial fibrillation (9.4%), heart failure (8.6%), corrected QT interval prolongation (8.0%), and cardiac ischemia (6.8%). Neither cardiovascular disease risk factors nor preexisting cardiac conditions were significantly associated with the development of cardiac complications. The cardiac complication group had a greater prevalence of high-grade parasitemia (>10%) (P < .001), longer median length of both hospital (P < .001) and intensive care unit stay (P < .001), and a higher mortality rate (P = .02) than the group without cardiac complications.
conclusionsCardiac complications of acute babesiosis are common and occurred in approximately one-fifth of this inpatient sample. Further investigation is needed to elucidate the relationship between babesiosis severity and cardiac outcomes.
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