ArticleThe British journal of surgery2022
Development and external validation of DISPAIR fistula risk score for clinically relevant postoperative pancreatic fistula risk after distal pancreatectomy.
Article in The British journal of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06141044 (PANDREAS. Prophylactic Abdominal Drainage vs no Drainage After Distal Pancreatectomy), which is not on this map. Cited by 28 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
PANDREAS. Prophylactic Abdominal Drainage vs no Drainage After Distal Pancreatectomy: a Multicentre Clinical Trial
Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Suture versus stapler in distal pancreatectomy and its impact on postoperative pancreatic fistula.Scientific reports · 2025Pooled it
- Pooled it
- Fibrin sealants for the prevention of postoperative pancreatic fistula following pancreatic surgery.The Cochrane database of systematic reviews · 2023Pooled it
- Comparison of endoscopic and radiologic drainage for symptomatic postoperative pancreatic fistula-associated collections after distal pancreatectomy.Surgical endoscopy · 2026Article
- Video-based OSATS and GEARS assessment of pancreatic transection and stump closure predicts clinically relevant pancreatic fistula after robotic distal pancreatectomy.Surgical endoscopy · 2026Article
- Area-based centralization of pancreatic surgery: a Hub-and-Spoke system balances patient proximity and quality of care.Updates in surgery · 2026Article
- Clinical feasibility analysis of reducing the incidence of pancreatic fistula after laparoscopic distal pancreatectomy by using a pancreatic duct stent to occlude the residual main pancreatic duct.Surgical endoscopy · 2026Article
- Integrative deep learning analysis of 2D and 3D body composition features for predicting postoperative pancreatic fistula after distal pancreatectomy.Annals of medicine · 2025Article
- Evaluation of external validity of the distal pancreatectomy fistula risk score (D-FRS) in a high-volume center.Surgical endoscopy · 2025Article
- Developing and validating a nomogram to forecast clinically relevant postoperative pancreatic fistula following distal pancreatectomy.Gland surgery · 2025Article
- Classification of postoperative pancreatic fistula after left pancreatectomy: international multicentre cohort study.BJS open · 2025Article
- Review
- Middle segment preserving pancreatectomy versus total pancreatectomy: a comparative analysis of short- and long-term outcomes.Surgery today · 2025Article
- Article
- International multicentre validation of the left pancreatectomy pancreatic fistula prediction models and development and validation of the combined DISPAIR-FRS prediction model.The British journal of surgery · 2025Article
- Reducing pancreatic fistula after left-sided pancreatectomy-the search continues.The British journal of surgery · 2025Article
- Advancements in postoperative pancreatic fistula: a comprehensive review of predictive factors, therapies, scoring systems and ongoing trials.eGastroenterology · 2025Review
- Topical application of Glauber's salt accelerates the absorption of abdominal fluid after pancreatectomy.BMC surgery · 2024Article
- Computed tomography-based radiomics and body composition analysis for predicting clinically relevant postoperative pancreatic fistula after pancreaticoduodenectomy.Gland surgery · 2024Article
- Meta-analysis and trial sequential analysis of pancreatic stump closure using a hand-sewn or stapler technique in distal pancreatectomy.Annals of hepato-biliary-pancreatic surgery · 2024Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHighly utilized risk scores for clinically relevant postoperative pancreatic fistula (CR-POPF) have guided clinical decision-making in pancreatoduodenectomy. However, none has been successfully developed for distal pancreatectomy. This study aimed to develop and validate a new fistula risk score for distal pancreatectomy.
methodsPatients undergoing distal pancreatectomy at Helsinki University Hospital, Finland from 2013 to 2021, and at Karolinska University Hospital, Sweden, from 2010 to 2020, were included retrospectively. The outcome was CR-POPF, according to the 2016 International Study Group of Pancreatic Surgery definition. Preoperative clinical demographics and radiological parameters such as pancreatic thickness and duct diameter were measured. A logistic regression model was developed, internally validated with bootstrapping, and the performance assessed in an external validation cohort.
resultsOf 668 patients from Helsinki (266) and Stockholm (402), 173 (25.9 per cent) developed CR-POPF. The final model consisted of three variables assessed before surgery: transection site (neck versus body/tail), pancreatic thickness at transection site, and diabetes. The model had an area under the receiver operating characteristic curve (AUROC) of 0.904 (95 per cent c.i. 0.855 to 0.949) after internal validation, and 0.798 (0.748 to 0.848) after external validation. The calibration slope and intercept on external validation were 0.719 and 0.192 respectively. Four risk groups were defined in the validation cohort for clinical applicability: low (below 5 per cent), moderate (at least 5 but below 30 per cent), high (at least 30 but below 75 per cent), and extreme (75 per cent or more). The incidences in these groups were 8.7 per cent (11 of 126), 22.0 per cent (36 of 164), 63 per cent (57 of 91), and 81 per cent (17 of 21) respectively.
conclusionThe DISPAIR score after distal pancreatectomy may guide decision-making and allow a risk-adjusted outcome comparison for CR-POPF.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.