Evidence map›Paper›PMID 35983454›Full record

ArticleJournal of Taibah University Medical Sciences2022

Long-term treatment of dentine with triple antibiotic paste promotes stem cell viability and attachment.

Samiya Riaz, Ahmad Azlina, Zuliani Mahmood, Aung T Htun

Open access · goldAbstract read
In one paragraph

Article in Journal of Taibah University Medical Sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Effect of Intracanal Medications on the Viability of Human Periodontal Ligament-Derived Mesenchymal Stem Cells.Australian endodontic journal : the journal of the Australian Society of Endodontology Inc · 2026
    Article
  2. Antibiotic approaches to endodontic regeneration.Biomaterial investigations in dentistry · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Samiya RiazPaediatric Dentistry Unit, School of Dental Sciences, Universiti Sains Malaysia, Health Campus Kubang Kerian, Kelantan, Malaysia.
Ahmad AzlinaBasic Sciences and Oral Biology Unit, School of Dental Sciences, Universiti Sains Malaysia, Health Campus Kubang Kerian, Kelantan, Malaysia.
Zuliani MahmoodPaediatric Dentistry Unit, School of Dental Sciences, Universiti Sains Malaysia, Health Campus Kubang Kerian, Kelantan, Malaysia.
Aung T HtunPaediatric Dentistry Unit, School of Dental Sciences, Universiti Sains Malaysia, Health Campus Kubang Kerian, Kelantan, Malaysia.
Universiti Sains Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Successful regenerative endodontic procedures in dental treatment are critically associated with complete disinfection of the root canal and require irrigants and medicaments. One factor for consideration is the biocompatibility of the medicament as this can affect the intracanal dentine and subsequently the dental stem cell viability required for the repair of the dentine-pulp complex. This in vitro study investigated the effect of a 4-week treatment of calcium hydroxide [Ca(OH) Methods: TAP consists of metronidazole, ciprofloxacin and minocycline. Dentine chips were prepared and treated with either Ca(OH) Results: DPSCs grown from dentine treated with TAP showed significantly higher cell viability than the Ca(OH) Conclusion: The treatment of dentine with TAP for 4 weeks provided a better microenvironment for the viability and attachment of DPSCs when compared to Ca(OH)

Indexed as

Cell viabilityDental pulp stem cellsIntracanal medicamentsIrrigated radicular dentineScanning electron microscope

Identifiers

PMID35983454
PMCPMC9356367
OpenAlexW4211240658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.