Evidence map›Paper›PMID 35983340›Full record

ArticleRadiologia brasileira

Magnetic resonance imaging at 3.0-T in postmenopausal osteoporosis: a prospective study and review of the literature.

Mirko Trentadue, Carlo Sozzi, Luca Idolazzi, Gianluigi Lazzarini, Riccardo Sante Murano, Davide Gatti, Maurizio Rossini, Enrico Piovan

Open access · diamondAbstract read
In one paragraph

Article in Radiologia brasileira. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Comparison of the value of VBQ scores for assessing abnormal bone mass based on DXA and QCT.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  2. Assessing lumbar vertebral bone quality: a methodological evaluation of CT and MRI as alternatives to traditional DEXA.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Mirko TrentadueRadiology Unit, Azienda ULSS 9 Scaligera, Hospital M. Magalini, Villafranca di Verona, Italy.ORCID 0000-0001-6615-6946
Carlo SozziSC Neuroradiology, ASST Carlo Poma, Mantova, Italy.ORCID 0000-0002-5942-7995
Luca IdolazziRheumatology Unit, Department of Medicine, University of Verona, Verona, Italy.ORCID 0000-0002-7254-4686
Gianluigi LazzariniIndependent Researcher, self-employed Occupational Medicine specialist, Peschiera del Garda, Italy.ORCID 0000-0001-5748-0699
Riccardo Sante MuranoRadiology Unit, Azienda ULSS 9 Scaligera, Hospital M. Magalini, Villafranca di Verona, Italy.ORCID 0000-0002-9476-0080
Davide GattiRheumatology Unit, Department of Medicine, University of Verona, Verona, Italy.ORCID 0000-0002-7471-3076
Maurizio RossiniRheumatology Unit, Department of Medicine, University of Verona, Verona, Italy.ORCID 0000-0001-9692-2293
Enrico PiovanSC Neuroradiology, ASST Carlo Poma, Mantova, Italy.ORCID 0000-0001-9850-3316
University of Verona · ITAzienda Ospedaliera Universitaria Integrata Verona · ITInstitute of Neurological Sciences · ITCasa di Cura Villa Garda · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To promote advanced research using magnetic resonance imaging (MRI) in the diagnosis of and screening for osteoporosis by looking for correlations among the T-scores measured by dual-energy X-ray absorptiometry (DEXA), the apparent diffusion coefficient (ADC) values on diffusion-weighted imaging (DWI), and the T1-weighted signal intensity values. Materials and Methods: This was a prospective study of postmenopausal women with no contraindications to MRI and no history of cancer who underwent DEXA within 30 days before or after the MRI examination. A 3.0-T scanner was used in order to acquire sagittal sequences targeting the lumbar spine. Results: Thirteen women underwent DEXA and MRI. In two cases, the MRI was discontinued early. Therefore, the final sample comprised 11 patients. The ADC values and T1-weighted signal intensity were found to be higher in patients with osteoporosis. However, among the patients > 60 years of age with osteoporosis, ADC values were lower and T1-weighted signal intensity was even higher. Conclusion: It is unlikely that MRI will soon replace DEXA for the diagnostic workup of osteoporosis. Although DWI and ADC mapping are useful for understanding the pathophysiology of osteoporosis, we believe that T1-weighted sequences are more sensitive than is DWI as a means of performing a qualitative analysis of vertebral alterations.

Indexed as

Bone marrow/pathologyMultiparametric magnetic resonance imaging/methodsOsteoporosisPostmenopauseVertebral body/pathology

Identifiers

PMID35983340
PMCPMC9380604
OpenAlexW4225279683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.