Evidence map›Paper›PMID 35983303›Full record

ArticleAntibody therapeutics2022

Use of Debye-Hückel-Henry charge measurements in early antibody development elucidates effects of non-specific association.

Joshua R Laber, Thomas M Laue, Dana I Filoti

Open access · goldAbstract read
In one paragraph

Article in Antibody therapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Joshua R LaberFormulation and Biologics Product Development, Nektar Therapeutics, 455 Mission Bay Boulevard South, San Francisco, CA 94158, USA.ORCID https://orcid.org/0000-0002-7572-4260
Thomas M LaueCarpenter Professor Emeritus, University of New Hampshire, Durham, NH 03824, USA.
Dana I FilotiAnalytical Research and Development, AbbVie, 100 Research Drive, Worcester, MA 01605, USA.ORCID https://orcid.org/0000-0003-0912-6657
AbbVie (United States) · USNektar Therapeutics (United States) · USUniversity of New Hampshire · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diffusion interaction parameter (

Indexed as

antibody developabilitycolloidal interactionsdiffusion interaction parameterdynamic light scatteringsurface charge

Identifiers

PMID35983303
PMCPMC9380711
OpenAlexW4288084879

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.