Evidence map›Paper›PMID 35983239›Full record

ArticlePalliative medicine reports2021

Hemostatic Effect of Palliative Radiation Therapy in Preventing Blood Transfusions from Bleeding Occurring within Advanced Gastric Cancer.

Norio Mitsuhashi, Hajime Ikeda, Yoshitaka Nemoto, Mayumi Kuronuma, Masahiro Kamiga, Yoshinori Hiroshima

Open access · goldAbstract read
In one paragraph

Article in Palliative medicine reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Hemostatic palliative radiotherapy for gastric cancer: A literature review.Technical innovations & patient support in radiation oncology · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Norio MitsuhashiCancer Board Division, Radiation Therapy Center, Hitachinaka General Hospital, Hitachinaka, Ibaraki, Japan.
Hajime IkedaCancer Board Division, Radiation Therapy Center, Hitachinaka General Hospital, Hitachinaka, Ibaraki, Japan.
Yoshitaka NemotoCancer Board Division, Radiation Therapy Center, Hitachinaka General Hospital, Hitachinaka, Ibaraki, Japan.
Mayumi KuronumaCancer Board Division, Radiation Therapy Center, Hitachinaka General Hospital, Hitachinaka, Ibaraki, Japan.
Masahiro KamigaDepartment of Palliative Care, amd Hitachinaka General Hospital, Hitachinaka, Ibaraki, Japan.
Yoshinori HiroshimaDepartment of Gastroenterology, Hitachinaka General Hospital, Hitachinaka, Ibaraki, Japan.
Hitachi General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To report the hemostatic effects of palliative radiation therapy (RT) for the prevention of blood transfusions (BT) in patients with advanced gastric cancer (AGC). Methods and Materials: Twenty-eight patients who received palliative three-dimensional conformal RT for hemostasis of gastric bleeding were retrospectively assessed in a study conducted in Japan. The median follow-up was 143.5 days. Changes in hemoglobin (Hb) levels were compared at the beginning of RT and four weeks later. Blood transfusion-free survival (BTFS) and overall survival (OS) were measured from the beginning of RT. Treatment toxicity was evaluated within 60 days of RT initiation. Results: No statistically significant decrease in Hb level was observed four weeks after RT. Twenty-eight patients did not receive BT within a month after RT, of whom three died within a month; 6/28 patients (21%) received BT at a median interval of 99.5 days following RT. The one-year BTFS and OS rates for all patients were 69% and 12%, respectively. The one-year BTFS was statistically significantly higher in 17 patients treated with a biologically effective dose (BED) Conclusions: Palliative RT is an effective treatment to prevent BT for bleeding occurring within AGC. Specifically, a fractionation regimen of 30 Gy in 10 fractions (a BED

Indexed as

advanced gastric cancerhemostatic effectradiation therapy

Identifiers

PMID35983239
PMCPMC9380884
OpenAlexW4200047679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.