Evidence map›Paper›PMID 35983014›Full record

ArticleClinicoEconomics and outcomes research : CEOR2022

Real-World Evaluation of Clinical Response and Long-Term Healthcare Resource Utilization Patterns Following Treatment with a Digital Therapeutic for Chronic Insomnia.

Felicia Forma, Tyler G Knight, Frances P Thorndike, Xiaorui Xiong, Rebecca Baik, Fulton F Velez, Yuri A Maricich, Daniel C Malone

Open access · goldAbstract read
In one paragraph

Article in ClinicoEconomics and outcomes research : CEOR, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Felicia FormaPear Therapeutics, Inc., Medical Affairs Department, Boston, MA, USA.
Tyler G KnightLabcorp Drug Development, Market Access Consulting Department, Gaithersburg, MD, USA.
Frances P ThorndikePear Therapeutics, Inc., Medical Affairs Department, Boston, MA, USA.
Xiaorui XiongPear Therapeutics, Inc., Medical Affairs Department, Boston, MA, USA.ORCID 0000-0001-7838-4524
Rebecca BaikLabcorp Drug Development, Market Access Consulting Department, Gaithersburg, MD, USA.
Fulton F VelezPear Therapeutics, Inc., Medical Affairs Department, Boston, MA, USA.ORCID 0000-0001-9054-5933
Yuri A MaricichPear Therapeutics, Inc., Medical Affairs Department, Boston, MA, USA.
Daniel C MaloneStrategic Therapeutics, LLC, Oro Valley, AZ, USA.
Pear Therapeutics (United States) · USLabCorp (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: This analysis evaluated insomnia severity and long-term impact on healthcare resource utilization (HCRU) and costs after treatment with Somryst Methods: Change from baseline in insomnia severity index (ISI) score was assessed using last observed ISI score. A pre/post analysis of claims data was conducted, comparing HCRU in patients with self-identified sleep problems who successfully initiated the therapeutic (index date) between June 1, 2016 and December 31, 2018. Results: A total of 248 patients were analyzed (median age 56.5 years, 57.3% female, mean ISI score 19.13, 52.4% treated with sleep aid medications pre-index). After 9 weeks, mean ISI score declined by 37.2% from baseline (19.1 vs 12.0), 58.8% of patients achieved ISI responder status (ISI score improved by =>7; NNT: 1.7), and 26.6% of patients achieved insomnia remission (ISI score <8; NNT for remission: 3.8). After two-year follow-up, post-index events were reduced (compared to 2 years pre-index) for emergency department visits (-53%; IRR: 0.47; 95% CI 0.27, 0.82; Conclusion: In a real-world cohort of patients with chronic insomnia, treatment with a digital therapeutic delivering CBT-I was associated with reductions in insomnia severity, emergency department visits, and net costs.

Indexed as

CBT-Ichronic insomniacognitive behavioral therapy for insomniaprescription digital therapeuticSHUTiSomryst

Identifiers

PMID35983014
PMCPMC9379126
OpenAlexW4294238704

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.