Evidence map›Paper›PMID 35983003›Full record

ReviewEvidence-based complementary and alternative medicine : eCAM2022

Type 2 Diabetes Mellitus (T2DM) and Carbohydrate Metabolism in Relation to T2DM from Endocrinology, Neurophysiology, Molecular Biology, and Biochemistry Perspectives.

Hilla Mills, Ronald Acquah, Nova Tang, Luke Cheung, Susanne Klenk, Ronald Glassen, Magali Pirson, Alain Albert, Duong Trinh Hoang, Thang Nguyen Van

RetractedOpen access · hybridAbstract readReviewRetracted Publication
In one paragraph

Review in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Hypoglycemic activity ofFrontiers in pharmacology · 2024
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Retrospective Case Analysis of 104 Cases of Talipes Equinus.Journal of environmental and public health · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Hilla MillsDepartment of Medical Science, University for Development, Accra, Ghana.ORCID https://orcid.org/0000-0003-2032-9279
Ronald AcquahDepartment of Medical Science, University for Development, Accra, Ghana.ORCID https://orcid.org/0000-0002-5375-6106
Nova TangRD Lab, The Hospital Institute for Hebal Research, Toluca 50200, MEX, Mexico.ORCID https://orcid.org/0000-0002-5745-3663
Luke CheungRD Lab, The Hospital Institute for Hebal Research, Toluca 50200, MEX, Mexico.ORCID https://orcid.org/0000-0003-2723-5910
Susanne KlenkResearch Institution of Clinical Biomedicine, Hospital University Medical Centre, Ulm 89000, Germany.ORCID https://orcid.org/0000-0002-4971-5192
Ronald GlassenResearch Institution of Clinical Biomedicine, Hospital University Medical Centre, Ulm 89000, Germany.ORCID https://orcid.org/0000-0003-3195-5718
Magali PirsonIndustrial Research Group, International College of Science and Technology, Route de Lennik 800, CP 590, Brussels 1070, Belgium.ORCID https://orcid.org/0000-0001-8468-3184
Alain AlbertIndustrial Research Group, International College of Science and Technology, Route de Lennik 800, CP 590, Brussels 1070, Belgium.ORCID https://orcid.org/0000-0003-1012-7331
Duong Trinh HoangClinical Analysis Lab, Center of Bio-Medicine, Hanoi, Vietnam.ORCID https://orcid.org/0000-0002-4463-4270
Thang Nguyen VanClinical Analysis Lab, Center of Bio-Medicine, Hanoi, Vietnam.ORCID https://orcid.org/0000-0003-1628-0011
University for Development Studies · GHUniversity Hospital Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 2 diabetes mellitus (T2DM) is a severe disease caused by metabolic disorders, particularly carbohydrate metabolism disorders. The disease is a fatal global trouble characterised by high prevalence rates, causing death, blindness, kidney failure, myocardial infarction, amputation of lower limps, and stroke. Biochemical metabolic pathways like glycolysis, gluconeogenesis, glycogenesis, and glycogenolysis are critical pathways that regulate blood glucose levels with the glucokinase (GK) enzyme playing a central role in glucose homeostasis. Any factor that perturbs the aforementioned biochemical pathways is detrimental. Endocrinological, neurophysiological, and molecular biological pathways that are linked to carbohydrate metabolism should be studied, grasped, and manipulated in order to alleviate T2DM global chaos. The challenge, howbeit, is that, since the body is an integration of systems that complement one another, studying one "isolated" system is not very useful. This paper serves to discuss endocrinology, neurophysiology, and molecular biology pathways that are involved in carbohydrate metabolism in relation to T2DM.

Identifiers

PMID35983003
PMCPMC9381199
OpenAlexW4290792273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.