Evidence map›Paper›PMID 35982903›Full record

ReviewInternational journal of biological sciences2022

Regulation of Adipose Thermogenesis and its Critical Role in Glucose and Lipid Metabolism.

Linghui Wang, Yanhao Qiu, Hao Gu, Mailin Gan, Yan Zhu, Kangping Zhu, Lei Chen, Ye Zhao, Lili Niu, Shunhua Zhang and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Linghui WangDepartment of Animal Science, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Yanhao QiuDepartment of Animal Science, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Hao GuDepartment of Animal Science, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Mailin GanDepartment of Animal Science, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Yan ZhuCollege of Life Science, China West Normal University, Nanchong 637009, Sichuan, PR China.
Kangping ZhuSichuan Dekon Livestock Foodstuff Group, Chengdu 610200, China.
Lei ChenDepartment of Animal Science, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Ye ZhaoDepartment of Animal Science, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Lili NiuDepartment of Animal Science, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Shunhua ZhangDepartment of Animal Science, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Xuewei LiDepartment of Animal Science, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Li ZhuDepartment of Animal Science, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Linyuan ShenDepartment of Animal Science, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Sichuan Agricultural University · CNWen's Food Group (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The function of the adipose tissue is influenced by complex interactions between genetics, epigenetics, and the environment, and its dysfunction can cause a variety of metabolic diseases, such as obesity or type 2 diabetes (T2D). The beige/brown adipose tissue plays a crucial role in regulating glucose and lipid metabolism by increasing energy metabolism to generate heat. The adipose tissue thermogenic program is a complex network that involves many signaling pathways regulated by coding RNAs (cRNAs) that encode transcription factor, and non-coding RNAs (ncRNAs) including microRNAs (miRNAs) and long noncoding RNAs (lncRNAs). This article discusses factors that regulate adipose tissue thermogenesis, including cRNAs and ncRNAs, and the important role of thermogenic adipose tissue in obesity-related metabolic syndrome. Several studies have shown that some cRNAs and ncRNAs can modulate the thermogenic function of adipose tissue in different ways. This article reviews the roles of cRNAs and ncRNAs in regulating thermogenesis in the beige/brown adipose tissue and the important role of the beige/brown adipose tissue in maintaining the balance of glucose and lipid metabolism in the body.

Indexed as

Diabetes Mellitus, Type 2Lipid MetabolismAdipose Tissue, BrownEnergy MetabolismGlucoseHumansObesityThermogenesisGlucoseBeige adiposeBrown adiposeCoding RNAmetabolic syndromeNon-coding RNAObesitythermogenesis

Identifiers

PMID35982903
PMCPMC9379406
OpenAlexW4288085769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.