Evidence map›Paper›PMID 35982888›Full record

ArticleInternational journal of biological sciences2022

Decrease of circARID1A retards glioblastoma invasion by modulating miR-370-3p/ TGFBR2 pathway.

Baisheng Li, Jiansheng Chen, Yi Wu, Honghai Luo, Yiquan Ke

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 24 citations in OpenAlex.

  1. Cell adhesion & migration · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Cells · 2025
    Article
  8. Review
  9. Article
  10. Exosomes in the Chemoresistance of Glioma: Key Point in Chemoresistance.Journal of cellular and molecular medicine · 2025
    Review
  11. Review
  12. Review
  13. Observational
  14. Review
  15. Article
  16. Review
  17. Review
  18. The Glioblastoma CircularRNAome.International journal of molecular sciences · 2023
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Baisheng LiThe National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
Jiansheng ChenDepartment of Neurosurgery, Huizhou Municipal Central Hospital, Huizhou Shi, China.
Yi WuDepartment of Neurosurgery, The Sixth Affiliated Hospital, South China University of Technology, Foshan 528200, China.
Honghai LuoDepartment of Neurosurgery, Huizhou Municipal Central Hospital, Huizhou Shi, China.
Yiquan KeThe National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
Huizhou Central People's Hospital · CNZhujiang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing evidence suggests that circular RNAs (circRNAs) are involved in regulating tumor biological activity. Glioblastoma (GBM) is one of the most lethal diseases characterized by highly aggressive proliferative and invasive behaviors. We aimed to explore how circRNAs influenced GBM biological activity. By circRNA array analysis we found that circARID1A was significantly up-regulated in GBM. Next, we found that circARID1A was up-regulated in GBM tissues and cell lines. Interfering with circARID1A inhibited the migration and invasion of a human GBM cell line U87. By performing dual-luciferase reporter assays, RNA pull-down and fluorescent

Indexed as

GlioblastomaMicroRNAsReceptor, Transforming Growth Factor-beta Type IIRNA, CircularCell Line, TumorCell MovementCell ProliferationGene Expression Regulation, NeoplasticHumansIn Situ Hybridization, FluorescenceMicroRNAsMIRN370 microRNA, humanReceptor, Transforming Growth Factor-beta Type IIRNA, CircularTGFBR2 protein, humancircARID1AexosomesglioblastomamiR-370-3pTGFBR2

Identifiers

PMID35982888
PMCPMC9379412
OpenAlexW4291131178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.