Evidence map›Paper›PMID 35982462›Full record

ArticleAnnals of general psychiatry2022

Vitamin D status and its correlation to depression.

Bashir Khan, Huma Shafiq, Seyyedha Abbas, Summeira Jabeen, Sikandar Ali Khan, Tayyaba Afsar, Ali Almajwal, Nawaf W Alruwaili, Dara Al-Disi, Sultan Alenezi and 2 more

Open access · goldAbstract read
In one paragraph

Article in Annals of general psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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  6. Oxidative Stress in Brain Function.Antioxidants (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 4 countries.

Bashir KhanInstitute of Basic Medical Sciences, Khyber Medical University Peshawar, Peshawar, Pakistan.
Huma ShafiqInstitute of Cellular Medicine, Newcastle University Medical School, Newcastle University United Kingdom, Newcastle, England.
Seyyedha AbbasInstitute of Basic Medical Sciences, Khyber Medical University Peshawar, Peshawar, Pakistan.
Summeira JabeenInstitute of Basic Medical Sciences, Khyber Medical University Peshawar, Peshawar, Pakistan.
Sikandar Ali KhanInstitute of Basic Medical Sciences, Khyber Medical University Peshawar, Peshawar, Pakistan.
Tayyaba AfsarDepartment of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Ali AlmajwalDepartment of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Nawaf W AlruwailiDepartment of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Dara Al-DisiDepartment of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Sultan AleneziInstitute of Cellular Medicine, Newcastle University Medical School, Newcastle University United Kingdom, Newcastle, England.
Zahida ParveenUniversity of Iceland, 101, Reykjavik, Iceland.
Suhail RazakDepartment of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia. smarazi@ksu.edu.sa.
King Saud University · SAKhyber Medical University · PKNewcastle University · GBUniversity of Iceland · IS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVitamin D can influence more than 200 genes in various tissues showing its credibility among the fat-soluble vitamins. Vitamin D deficiency is directly proportional to major clinical conditions such as cardiovascular diseases, diabetes, malignancy, and multiple sclerosis. This study was conducted to determine the vitamin D level of individuals and its association with depression.

methodsVitamin D levels of 100 healthy and 100 depressed subjects were determined. The isolated subjects were screened on the Beck Depression Inventory (BDI) scale and divided into three groups according to their age. Group-I comprised subjects of age 20 years and below, Group-II included subjects of age 21 to 60, and Group-III comprised subjects of ≥ 61 years of age. A sufficient level of vitamin D in normal subjects was noted, while mild deficiency of vitamin D status was observed in depressed subjects.

resultsOur study has reported a higher percentage of vitamin D deficiency in the Peshawar region. The results of our study indicated that depression was common in individuals having vitamin D deficiency.

conclusionsThe study showed a very high frequency of vitamin D deficiency in subjects with depression in Peshawar, Pakistan. The deficiency of vitamin D was observed more in females as compared to males. Further studies should explicate whether the highly widespread vitamin D deficiency could be cost-effectively treated as part of preventive or treatment interventions for depression.

Indexed as

Beck depression inventoryTyrosine hydroxylase and depressionVitamin D

Identifiers

PMID35982462
PMCPMC9389668
OpenAlexW4292248870

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.