SynthesisNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2022
N200 and P300 component changes in Parkinson's disease: a meta-analysis.
Synthesis in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 26 citations in OpenAlex.
- Assessment of balance, sleep quality, and depression in relation to attention in Parkinson's disease: A cross-sectional P300 study.Sao Paulo medical journal = Revista paulista de medicina · 2026Trial
- Distinct effects of long-term Tai Chi Chuan and aerobic exercise interventions on motor and neurocognitive performance in early-stage Parkinson's disease: a randomized controlled trial.European journal of physical and rehabilitation medicine · 2024Trial
- Dissociating the hierarchical processing of perceptual and food category information under different task demands.Psychonomic bulletin & review · 2026Article
- Serum albumin and uric acid: biomarkers of neurocognitive and physical function in early Parkinson's disease.Experimental brain research · 2026Article
- N200 and P300 as neurophysiological markers of the cognitive continuum in Parkinson's disease: insights from an inhibitory control task.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Studying neurocognitive systems for sustained attention in neurogeriatric patients: protocol of the SENSE-AGE study.Frontiers in aging neuroscience · 2026Article
- Effects of acupuncture and exercise on EEG characteristics and cognitive control in college students with high procrastination tendency.Frontiers in public health · 2026Article
- The use of electroencephalography in neurodegenerative disease and its utility in dementia.NPJ dementia · 2026Review
- Research on the Behavioral and ERP Characteristics Induced by the Availability Heuristic in Intuitive Decision-Making.Sensors (Basel, Switzerland) · 2025Article
- Key shifts in frontoparietal network activity in Parkinson's disease.NPJ Parkinson's disease · 2025Article
- Sleep efficiency and event-related potentials in patients with depression: the mediating role of serum C-reactive protein.Frontiers in psychiatry · 2025Article
- Biomarkers for cognitive impairment in alpha-synucleinopathies: an overview of systematic reviews and meta-analyses.NPJ Parkinson's disease · 2024Article
- Subjective cognitive decline in healthy older adults is associated with altered processing of negative versus positive feedback in a probabilistic learning task.Frontiers in psychology · 2024Article
- Pathobiology of Cognitive Impairment in Parkinson Disease: Challenges and Outlooks.International journal of molecular sciences · 2023Review
- Differences in EEG Event-Related Potentials during Dual Task in Parkinson's Disease Carriers and Non-Carriers of the G2019S-LRRK2 Mutation.Sensors (Basel, Switzerland) · 2023Article
- Evaluation of Event-Related Potentials in Assessing Cognitive Functions of Adult Patients with Epilepsy of Unknown Etiology.Journal of clinical medicine · 2023Article
- Effect of 12-week Practice of Anulom Vilom Pranayama as Adjunctive Therapy on the Cardiac Autonomic Balance, Cognition, Psychological Status, and Quality of Life in Individuals with Mild-to-Moderate Parkinson's Disease: A Randomized Controlled Trial.International journal of yogaArticle
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundCognitive impairment can seriously affect the quality of life of Parkinson's disease (PD) patients. Although numerous studies showed that N200, P300 latency and amplitude are correlated with cognitive functions, there is a sufficient amount of controversial results. Therefore, it is necessary to conduct a meta-analysis of N200, P300 latency and amplitude data of event-related potential (ERP) in PD.
methodsWe systematically searched on PubMed and Web of Science for PD-related ERP studies published before December 2021. Standard mean difference (SMD) and 95% confidence interval (CI) estimates of N200 and P300 components were compared among PD patients, PD dementia (PDD) patients, PD non-dementia (PDND) patient, and healthy control (HC).
resultsOur meta-analysis showed prolonged N200 latency at the Fz, Cz electrode sites, prolonged P300 latency at the Fz sites in PD patients, compared to HC; prolonged N200 latency at the Cz, Pz electrode sites in PDND patients, compared to HC; prolonged P300 latency at the Cz site in PDD patients, compared to PDND patients; and reduced P300 amplitude at the Fz electrode site in PDND patients, compared to HC.
conclusionsN200 and P300 component may be potential electrophysiological biomarkers of early cognitive impairment in PD patients. Future studies are needed to confirm this conclusion. Estimates of N200 and P300 component can be a valuable support for clinicians in diagnosis of early cognitive impairment in PD patients due to the simplicity and non-invasiveness of the procedure.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.