ArticleNature plants2022
Tethering of cellulose synthase to microtubules dampens mechano-induced cytoskeletal organization in Arabidopsis pavement cells.
Article in Nature plants, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 56 citations in OpenAlex.
- Stress-induced MAPK (SIMK)-dependent organization of microtubules in alfalfa.Molecular horticulture · 2026Article
- Differential cellulose distribution drives polarized growth of cotton fibers.Nature communications · 2026Article
- A Guide to Reproducible Cellulose Synthase Density and Speed Measurements inBio-protocol · 2026Article
- Best practices in plant fluorescence imaging and reporting: A primer.The Plant cell · 2025Review
- COBRA-LIKE4 modulates cellulose synthase velocity and facilitates cellulose deposition in the secondary cell wall.Plant physiology · 2024Article
- FERONIA adjusts CC1 phosphorylation to control microtubule array behavior in response to salt stress.Science advances · 2024Article
- A cellulose synthesis inhibitor affects cellulose synthase complex secretion and cortical microtubule dynamics.Plant physiology · 2024Article
- Spatiotemporally distinct responses to mechanical forces shape the developing seed of Arabidopsis.The EMBO journal · 2024Article
- Disrupting cell wall integrity impacts endomembrane trafficking to promote secretion over endocytic trafficking.Journal of experimental botany · 2024Article
- The plant cell wall-dynamic, strong, and adaptable-is a natural shapeshifter.The Plant cell · 2024Review
- Structure and growth of plant cell walls.Nature reviews. Molecular cell biology · 2024Review
- Cell geometry regulates tissue fracture.Nature communications · 2023Article
- Spatial consistency of cell growth direction during organ morphogenesis requires CELLULOSE SYNTHASE INTERACTIVE1.Cell reports · 2023Article
- High-throughput characterization of cortical microtubule arrays response to anisotropic tensile stress.BMC biology · 2023Article
- The Arabidopsis thaliana integrin-like gene AT14A improves drought tolerance in Solanum lycopersicum.Journal of plant research · 2023Article
- Microtubule Regulation in Plants: From Morphological Development to Stress Adaptation.Biomolecules · 2023Review
- Mechano-chemical regulation of complex cell shape formation: Epidermal pavement cells-A case study.Quantitative plant biology · 2023Review
- Microtubule nucleation complex behavior is critical for cortical array homogeneityProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Mechanosensing, from forces to structures.Frontiers in plant science · 2022Review
- Auxin Signaling Mediated Spatial Accommodation Mechanisms During Lateral Root Development.Physiologia plantarumReview
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 3 countries.
Funding
Abstract
Mechanical forces control development in plants and animals, acting as cues in pattern formation and as the driving force of morphogenesis. In mammalian cells, molecular assemblies residing at the interface of the cell membrane and the extracellular matrix play an important role in perceiving and transmitting external mechanical signals to trigger physiological responses. Similar processes occur in plants, but there is little understanding of the molecular mechanisms and their genetic basis. Here, we show that the number and movement directions of cellulose synthase complexes (CSCs) at the plasma membrane vary during initial stages of development in the cotyledon epidermis of Arabidopsis, closely mirroring the microtubule organization. Uncoupling microtubules and CSCs resulted in enhanced microtubule co-alignment as caused by mechanical stimuli driven either by cell shape or by tissue-scale physical perturbations. Furthermore, micromechanical perturbation resulted in depletion of CSCs from the plasma membrane, suggesting a possible link between cellulose synthase removal from the plasma membrane and microtubule response to mechanical stimuli. Taken together, our results suggest that the interaction of cellulose synthase with cortical microtubules forms a physical continuum between the cell wall, plasma membrane and the cytoskeleton that modulates the mechano-response of the cytoskeleton.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.