ArticleJournal of perinatology : official journal of the California Perinatal Association2022
Impact of multiple intubation attempts on adverse tracheal intubation associated events in neonates: a report from the NEAR4NEOS.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06757543 (A Stepped Wedge Cluster Randomised Trial Of Video Versus Direct Laryngoscopy For Intubation Of Newborn Infants), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Stepped Wedge Cluster Randomised Trial Of Video Versus Direct Laryngoscopy For Intubation Of Newborn Infants
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Video vs. direct laryngoscopy for tracheal intubation in neonates: a meta-analysis.Frontiers in pediatrics · 2025Pooled it
- Airway management and postoperative respiratory recovery after intravitreal injection in preterm infants.Pediatric research · 2026Article
- Pragmatic Respiratory Stabilization During Neonatal Intubation-What Does this Trial Add for Indian NICUs?Indian pediatrics · 2026Article
- Impact of attending neonatologist presence on neonatal intubation success and adverse events: a cohort study.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Web-based versus simulation-based refresher training in newborn life support: A randomized multicenter noninferiority controlled trial.Resuscitation plus · 2026Article
- Complementary views: addressing blind spots in the direct versus video laryngoscopy debate.BMJ paediatrics open · 2026Article
- Corrective steps during neonatal mask ventilation - a narrative review of the evidence behind the MR SOPA acronym.Resuscitation plus · 2026Review
- Neonatal endotracheal intubation: development of a comprehensive educational program for procedural skills.Pediatric research · 2026Review
- Deep learning to assess laryngoscope insertion depth during neonatal intubation with video laryngoscopy.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Impact of attending neonatologist presence on neonatal intubation success and adverse events: a cohort study.Research square · 2025Article
- Confirmation of successful supraglottic airway device placement in neonates using a respiratory function monitor.Pediatric research · 2025Article
- Neonatal Tracheal Intubation in the NICU: A Literature Review.Healthcare (Basel, Switzerland) · 2025Review
- Outcomes, safety and health economics of introduction of video laryngoscopy-assisted less invasive surfactant administration.Journal of perinatology : official journal of the California Perinatal Association · 2025Article
- Association between video laryngoscopy characteristics and successful neonatal tracheal intubation: a prospective study.Archives of disease in childhood. Fetal and neonatal edition · 2024Article
- Airway management in the paediatric difficult intubation registry: a propensity score matched analysis of outcomes over time.EClinicalMedicine · 2024Article
- I-gel Plus acts as a superior conduit for fiberoptic intubation than standard i-gel.Scientific reports · 2023Article
- Retrospective consent for neonatal intubations. Going with the flow?Journal of perinatology : official journal of the California Perinatal Association · 2023Article
- Design and Superior Performance of a New Endotracheal Tube to Avoid the Asphyxiation of Premature Infants.Cureus · 2023Article
- Success rates and adverse events during neonatal intubation: Lessons learned from an international registry.Seminars in fetal & neonatal medicine · 2023Review
- Strategies to Improve Neonatal Intubation Safety by Preventing Endobronchial Placement of the Tracheal Tube-Literature Review and Experience at a Tertiary Center.Children (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 15 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the relationship between number of attempts and adverse events during neonatal intubation. STUDY
designA retrospective study of prospectively collected data of intubations in the delivery room and NICU from the National Emergency Airway Registry for Neonates (NEAR4NEOS) in 17 academic centers from 1/2016 to 12/2019. We examined the association between tracheal intubation attempts [1, 2, and ≥3 (multiple attempts)] and clinical adverse outcomes (any tracheal intubation associated events (TIAE), severe TIAE, and severe oxygen desaturation).
resultsOf 7708 intubations, 1474 (22%) required ≥3 attempts. Patient, provider, and practice factors were associated with higher TI attempts. Increasing intubation attempts was independently associated with a higher risk for TIAE. The adjusted odds ratio for TIAE and severe oxygen desaturation were significantly higher in TIs with 2 and ≥3 attempts than with one attempt.
conclusionThe risk of adverse safety events during intubation increases with the number of intubation attempts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.