Evidence map›Paper›PMID 35982216›Full record

ReviewEuropean journal of clinical nutrition2023

Protective role of zinc in the pathogenesis of respiratory diseases.

Rumei Luan, Dongyan Ding, Qianfei Xue, Han Li, Yujuan Wang, Junling Yang

Open access · bronzeAbstract readReview
In one paragraph

Review in European journal of clinical nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Deciphering the Tenascin-C Nexus: A Comprehensive Review of Its Involvement in Chronic Respiratory Diseases.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025
    Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rumei LuanDepartment of Respiratory Medicine, the Second Hospital of Jilin University, Changchun, China.ORCID 0000-0002-2581-8920
Dongyan DingDepartment of Respiratory Medicine, the Second Hospital of Jilin University, Changchun, China.
Qianfei XueHospital of Jilin University, Changchun, China.
Han LiDepartment of Respiratory Medicine, the Second Hospital of Jilin University, Changchun, China.
Yujuan WangDepartment of Respiratory Medicine, the Second Hospital of Jilin University, Changchun, China.
Junling YangDepartment of Respiratory Medicine, the Second Hospital of Jilin University, Changchun, China. junling@jlu.edu.cn.ORCID 0000-0001-8360-2901
Second Affiliated Hospital of Jilin University · CNJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Respiratory diseases remain a major cause of morbidity and mortality worldwide. An imbalance of zinc, an essential trace element, is associated with a variety of lung diseases. We reviewed and summarized recent research (human subjects, animal studies, in vitro studies) on zinc in respiratory diseases to explore the protective mechanism of zinc from the perspective of regulation of oxidative stress, inflammation, lipid metabolism, and apoptosis. In the lungs, zinc has anti-inflammatory, antioxidant, and antiviral effects; can inhibit cancer cell migration; can regulate lipid metabolism and immune cells; and exerts other protective effects. Our comprehensive evaluation highlights the clinical and experimental effects of zinc in the pathogenesis of respiratory diseases. Our analysis also provides insight into the clinical application of zinc-targeted therapy for respiratory diseases.

Indexed as

Respiratory Tract DiseasesTrace ElementsAnimalsAntioxidantsHumansOxidative StressZincAntioxidantsTrace ElementsZinc

Identifiers

PMID35982216
PMCPMC9387421
OpenAlexW4293828925

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.