Evidence map›Paper›PMID 35981749›Full record

ArticleBMJ case reports2022

Extensive actinomycosis with intracranial and mediastinal involvement: a therapeutic challenge.

Farzana Ansari, Anil Budania, Meenakshi Rao, Taruna Yadav

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Farzana AnsariPacific Medical College & Hospital, Udaipur, Rajasthan, India.
Anil BudaniaDermatology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India anilbuddy25@gmail.com.
Meenakshi RaoPathology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.ORCID http://orcid.org/0000-0003-1310-2578
Taruna YadavDiagnostic and Interventional Radiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.ORCID http://orcid.org/0000-0002-3644-6093

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Central nervous system (CNS) involvement by actinomycosis is rare, seen in 2%-3% cases. It mostly spreads to CNS by haematogenous route from a distant primary site such as oral cavity, lung, abdomen or pelvis. Direct CNS extension can also occur. It mostly presents as brain abscess, meningoencephalitis, actinomycetoma, subdural empyema and epidural abscess. We report one case of extensive actinomycosis having intra and extraparenchymal CNS, spinal canal, retropharyngeal and mediastinal involvement. Due to such widespread extension and involvement of vital areas, complete surgical debulking was not possible. In addition to therapeutic resistance to conventional antibiotics, repetitive negative cultures posed significant difficulty in the case management.

Indexed as

ActinomycosisBrain AbscessEmpyema, SubduralEpidural AbscessMeningoencephalitisHumansDermatologyInfection (neurology)NeuroimagingPathology

Identifiers

PMID35981749
PMCPMC9394199

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.