Evidence map›Paper›PMID 35981537›Full record

ArticleCurrent biology : CB2022

A thermometer circuit for hot temperature adjusts Drosophila behavior to persistent heat.

Michael H Alpert, Hamin Gil, Alessia Para, Marco Gallio

Open access · greenAbstract read
In one paragraph

Article in Current biology : CB, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 31 citations in OpenAlex.

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  7. A functional clock in only two dorsal clock neurons is sufficient to restore the basal circadian activity pattern ofProceedings of the National Academy of Sciences of the United States of America · 2025
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  16. Activity Monitoring for Analysis of Sleep inCold Spring Harbor protocols · 2024
    Article
  17. Integration of photoperiodic and temperature cues by the circadian clock to regulate insect seasonal adaptations.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Michael H AlpertDepartment of Neurobiology, Northwestern University, Evanston, IL 60208, USA.
Hamin GilDepartment of Neurobiology, Northwestern University, Evanston, IL 60208, USA.
Alessia ParaDepartment of Neurobiology, Northwestern University, Evanston, IL 60208, USA.
Marco GallioDepartment of Neurobiology, Northwestern University, Evanston, IL 60208, USA. Electronic address: marco.gallio@northwestern.edu.
Northwestern University · US

Funding

TRAINING GRANT IN SLEEP RESEARCHT32HL007909 · NHLBI · NORTHWESTERN UNIVERSITY · PI FRED W TUREK, Phyllis C. Zee · 1998 to 2026
$9.2M
Neurogenetic Approaches to Study Directed Behavior in DrosophillaR01NS086859 · NINDS · NORTHWESTERN UNIVERSITY · PI Marco Gallio · 2014 to 2026
$5.0M
Re-engineering Connectivity in the Drosophila BrainR21EY031849 · NEI · NORTHWESTERN UNIVERSITY · PI GALLIO, MARCO · 2020 to 2020
$477k
NEI NIH HHS R21 EY031849NHLBI NIH HHS T32 HL007909NINDS NIH HHS R01 NS086859
6 · The paper itself

Abstract

Small poikilotherms such as the fruit fly Drosophila depend on absolute temperature measurements to identify external conditions that are above (hot) or below (cold) their preferred range and to react accordingly. Hot and cold temperatures have a different impact on fly activity and sleep, but the circuits and mechanisms that adjust behavior to specific thermal conditions are not well understood. Here, we use patch-clamp electrophysiology to show that internal thermosensory neurons located within the fly head capsule (the AC neurons

Indexed as

DrosophilaDrosophila ProteinsAnimalsCircadian RhythmDrosophila melanogasterHot TemperatureTemperatureThermometersDrosophila ProteinsAC neuronscircadian rhythmsclock neuronsdaytime sleepDrosophilaelectrophysiologyLPNssleep and activitytemperaturethermosensation

Identifiers

PMID35981537
PMCPMC9529852
OpenAlexW4292110700

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.