Evidence map›Paper›PMID 35981522›Full record

ArticleNeuron2022

Live, die, or regenerate? New insights from multi-omic analyses.

Nicole Y Tsai, Derek S Welsbie, Xin Duan

Open access · greenAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuron, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nicole Y TsaiDepartment of Ophthalmology, University of California San Francisco, San Francisco, CA, USA.
Derek S WelsbieDepartment of Ophthalmology, University of California San Diego, San Diego, CA, USA.
Xin DuanDepartment of Ophthalmology, University of California San Francisco, San Francisco, CA, USA. Electronic address: xin.duan@ucsf.edu.
University of California, San Francisco · USUniversity of California San Diego · US

Funding

Mechanisms Underlying Type II Cadherin Guided Assembly of Retinal CircuitsR01EY030138 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Xin Duan · 2020 to 2026
$3.2M
Kinase Multitargeting for Glaucoma NeuroprotectionR01EY029342 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Derek Stuart Welsbie · 2018 to 2026
$3.2M
Investigating the Role of Nephronectin in Establishing Retinotectal Circuit SpecificityF30EY033201 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI TSAI, NICOLE Y · 2021 to 2024
$184k
NEI NIH HHS F30 EY033201NEI NIH HHS R01 EY029342NEI NIH HHS R01 EY030138
6 · The paper itself

Abstract

In this issue of Neuron, three studies establish new strategies to uncover mediators of retinal neuroprotection and optic nerve regeneration. Tian et al. (2022) carry out a multi-omics screen and identify transcriptional regulators of axon injury signaling leading to cell death; Jacobi et al. (2022) and Li et al. (2022) combine retrograde tracing and single-cell RNA-seq (scRNA-seq) to uncover molecular targets for axon regeneration.

Indexed as

Optic Nerve InjuriesAxonsHumansNerve RegenerationRetinaRetinal Ganglion Cells

Identifiers

PMID35981522
PMCPMC9521179
OpenAlexW4292110659

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.