Evidence map›Paper›PMID 35981285›Full record

ArticleJournal of agricultural and food chemistry2022

Lunularin Producers versus Non-producers: Novel Human Metabotypes Associated with the Metabolism of Resveratrol by the Gut Microbiota.

Carlos E Iglesias-Aguirre, Fernando Vallejo, David Beltrán, Elena Aguilar-Aguilar, Julio Puigcerver, Mateo Alajarín, José Berná, María V Selma, Juan Carlos Espín

Open access · hybridAbstract read
In one paragraph

Article in Journal of agricultural and food chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  4. Food & function · 2026
    Article
  5. Review
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  7. Article
  8. Article
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  10. (Poly)phenol-gut microbiota interactions and their impact on human health.Current opinion in clinical nutrition and metabolic care · 2025
    Review
  11. Microbial metabolism of host-derived antioxidants.Current opinion in chemical biology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Carlos E Iglesias-AguirreLaboratory of Food & Health, Research Group on Quality, Safety, and Bioactivity of Plant Foods, CEBAS-CSIC, Campus de Espinardo, Murcia 30100, Spain.
Fernando VallejoLaboratory of Food & Health, Research Group on Quality, Safety, and Bioactivity of Plant Foods, CEBAS-CSIC, Campus de Espinardo, Murcia 30100, Spain.
David BeltránLaboratory of Food & Health, Research Group on Quality, Safety, and Bioactivity of Plant Foods, CEBAS-CSIC, Campus de Espinardo, Murcia 30100, Spain.
Elena Aguilar-AguilarNutrition and Clinical Trials Unit, GENYAL Platform, IMDEA-Food Institute, CEI UAM + CSIC, Madrid 28049, Spain.
Julio PuigcerverDepartment of Organic Chemistry, Faculty of Chemistry, University of Murcia, Murcia 30100, Spain.ORCID 0000-0001-8824-2773
Mateo AlajarínDepartment of Organic Chemistry, Faculty of Chemistry, University of Murcia, Murcia 30100, Spain.ORCID 0000-0002-7112-5578
José BernáDepartment of Organic Chemistry, Faculty of Chemistry, University of Murcia, Murcia 30100, Spain.ORCID 0000-0001-7775-3703
María V SelmaLaboratory of Food & Health, Research Group on Quality, Safety, and Bioactivity of Plant Foods, CEBAS-CSIC, Campus de Espinardo, Murcia 30100, Spain.ORCID 0000-0002-6780-974X
Juan Carlos EspínLaboratory of Food & Health, Research Group on Quality, Safety, and Bioactivity of Plant Foods, CEBAS-CSIC, Campus de Espinardo, Murcia 30100, Spain.ORCID 0000-0002-1068-8692
Centro de Edafología y Biología Aplicada del Segura · ESUniversidad de Murcia · ESMadrid Institute for Advanced Studies · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe here for the first time the consistent observation of two metabotypes associated with resveratrol metabolism by the human gut microbiota, that is, lunularin (LUNU)-producers and LUNU non-producers. In healthy volunteers (

Indexed as

Gastrointestinal MicrobiomeStilbenesBibenzylsFemaleHumansPhenolsResveratrolBibenzylslunularinPhenolsResveratrolStilbenesgut microbiotainterindividual variabilitylunularinmetabotyperesveratrol

Identifiers

PMID35981285
PMCPMC9449969
OpenAlexW4293805254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.