Evidence map›Paper›PMID 35980967›Full record

ArticlePloS one2022

Medication regimen complexity and its association with adherence and blood pressure control among hypertensive patients at selected hospitals of South Gondar Zone: A hospital based cross sectional study.

Taklo Simeneh Yazie, Workneh Ebabu Mengistu, Zemen Asmare, Abebe Muche Belete, Assefa Agegnehu Teshome, Yohannes Shumet Yimer

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Taklo Simeneh YazieDepartment of Pharmacy, Pharmacology and Toxicology Unit, College of Health Sciences, Debre Tabor University, Debre Tabor, Amhara, Ethiopia.ORCID 0000-0003-1218-5826
Workneh Ebabu MengistuSchool of Medicine, College of Health Sciences, Debre Tabor University, Debre Tabor, Amhara, Ethiopia.
Zemen AsmareSchool of Medicine, College of Health Sciences, Debre Tabor University, Debre Tabor, Amhara, Ethiopia.
Abebe Muche BeleteDepartment of Medicine, College of Medicine and Health Sciences, Debre Berhan University, Debre Berhan, Amhara, Ethiopia.
Assefa Agegnehu TeshomeDepartment of Biomedical Science, College of Health Sciences, Debre Tabor University, Debre Tabor, Amhara, Ethiopia.
Yohannes Shumet YimerDepartment of Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, Amhara, Ethiopia.
Debre Tabor University · ETDebre Berhan University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDespite the availability of effective antihypertensive medications, blood pressure (BP) control is suboptimal. High medication regimen complexity index (MRCI) is known to reduce adherence and may be the reason for poor BP control. However, there is no data in the present study areas. Hence, the aim of this study was to assess MRCI and its association with adherence and BP control among hypertensive patients at selected hospitals of South Gondar Zone.

methodsA hospital based cross sectional study was conducted from December 1, 2020 to February 30, 2021 at selected hospitals of South Gondar Zone. Medication regimen complexity and adherence was evaluated using 65-item validated tool called MRCI (Text removed at time of retraction. See retraction notice for more information.). Multivariable logistic regression analysis was done to determine the association between predictive and outcome variables.

resultsAbout 3.3% of participants were classified as having high HTN specific MRCI whereas 34.75% of participants were classified as having high patient level MRCI. (Text removed at time of retraction. See retraction notice for more information.) Being illiterate, and having low HTN MRCI were more likely to have controlled BP in adjusted analyses. On the contrary, (Text removed at time of retraction. See retraction notice for more information.) not having health insurance, and having lower monthly income were less likely to have controlled BP.

conclusionA considerable proportion of patients had high MRCI. Having low HTN MRCI was more likely to have controlled BP. Simplification of a complex medication regimen for patients with HTN should be sought by physicians and pharmacists to improve BP control.

Indexed as

HypertensionAntihypertensive AgentsBlood PressureCross-Sectional StudiesHospitalsHumansMedication AdherenceAntihypertensive Agents

Identifiers

PMID35980967
PMCPMC9387796
OpenAlexW4292219993

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.