Evidence map›Paper›PMID 35980771›Full record

ArticleJournal of cutaneous pathology2023

Perianal Paget disease associated with non-invasive colorectal adenoma.

Zhibo Zuo, Wanxin Wu, Xin Li, Lin Zhang, Jingyu Wang, Zhiqin Guo, Shaoqing Hu, Qi Zhang

Open access · hybridAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cutaneous pathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zhibo ZuoDepartment of Pathology, First Hospital of Jiaxing, Jiaxing, China.ORCID https://orcid.org/0000-0002-3222-4530
Wanxin WuDepartment of Pathology, First Hospital of Jiaxing, Jiaxing, China.
Xin LiDepartment of Pathology, First Hospital of Jiaxing, Jiaxing, China.
Lin ZhangDepartment of Pathology, First Hospital of Jiaxing, Jiaxing, China.
Jingyu WangDepartment of Pathology, First Hospital of Jiaxing, Jiaxing, China.
Zhiqin GuoDepartment of Pathology, First Hospital of Jiaxing, Jiaxing, China.
Shaoqing HuDepartment of Pathology, First Hospital of Jiaxing, Jiaxing, China.
Qi ZhangGraduate School of Nursing, Huzhou University, Huzhou, China.
First Hospital of Jiaxing · CNHuzhou University · CN

Funding

Jiaxing Municipal Science and Technology Project 2021AD30160
6 · The paper itself

Abstract

Perianal skin Paget disease (PPD) is an unusual subtype of extramammary Paget disease, which is usually caused by a primary intraepithelial adnexal tumor and secondary spread from colorectal adenocarcinoma. The reports of secondary PPD associated with non-invasive colorectal adenoma are rare. We report a rare case of non-invasive colorectal-adenoma-associated PPD. In this case, the intraepithelial Paget cells of perianal skin manifested with colorectal phenotype by immunohistochemistry, and adjacent adenomas had high-grade intraepithelial neoplasia but not invasion. Although this is a rare manifestation of PPD, understanding this phenomenon is important to prevent overdiagnosis and invasive overtreatment. Clinical management is variable and, therefore, close follow-up examination is necessary.

Indexed as

AdenocarcinomaAnus NeoplasmsPaget Disease, ExtramammarySkin NeoplasmsHumansSkinadenomainvasive carcinomaPaget diseaseperianal

Identifiers

PMID35980771
PMCPMC10087263
OpenAlexW4292248546

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.