Evidence map›Paper›PMID 35980456›Full record

ArticleActa neuropathologica2022

Selective tau seeding assays and isoform-specific antibodies define neuroanatomic distribution of progressive supranuclear palsy pathology arising in Alzheimer's disease.

David G Coughlin, Vanessa S Goodwill, Heidi G Standke, Yongya Kim, Nicolas Coley, Donald P Pizzo, Douglas Galasko, Allison Kraus, Annie Hiniker

Open access · hybridAbstract read
In one paragraph

Article in Acta neuropathologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Fluid biomarkers in atypical Parkinsonism: current state and future perspectives.Journal of neural transmission (Vienna, Austria : 1996) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

David G CoughlinDepartments of Neurosciences, University of California, San Diego, USA.
Vanessa S Goodwill *Departments of Pathology, University of California San Diego, 9500 Gilman Drive, La Jolla, San Diego, CA, 92093-0612, USA.
Heidi G Standke *Department of Pathology, Case Western Reserve University School of Medicine, 2103 Cornell Road, Cleveland, OH, 44106, USA.
Yongya KimDepartments of Pathology, University of California San Diego, 9500 Gilman Drive, La Jolla, San Diego, CA, 92093-0612, USA.
Nicolas ColeyDepartments of Pathology, University of California San Diego, 9500 Gilman Drive, La Jolla, San Diego, CA, 92093-0612, USA.
Donald P PizzoDepartments of Pathology, University of California San Diego, 9500 Gilman Drive, La Jolla, San Diego, CA, 92093-0612, USA.
Douglas GalaskoDepartments of Neurosciences, University of California, San Diego, USA.
Allison Kraus *Department of Pathology, Case Western Reserve University School of Medicine, 2103 Cornell Road, Cleveland, OH, 44106, USA. Allison.kraus@case.edu.ORCID http://orcid.org/0000-0001-8477-0894
Annie Hiniker *Departments of Pathology, University of California San Diego, 9500 Gilman Drive, La Jolla, San Diego, CA, 92093-0612, USA. ahiniker@health.ucsd.edu.ORCID http://orcid.org/0000-0002-0055-6610
University of California San Diego · USCornell University · US

Funding

UCSD Shiley-Marcos Alzheimer's Disease Research Center P30P30AG062429 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JAMES B BREWER · 2019 to 2026
$34.9M
Peripheral Tissue Biomarker for Premorten Diagnosis of Lewy Body DementiaR01NS118760 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CHEN, SHU G., KRAUS, ALLISON L · 2020 to 2025
$7.4M
Skin biomarkers for diagnosing and characterizing AD and ADRDR01AG067607 · NIA · CASE WESTERN RESERVE UNIVERSITY · PI CHEN, SHU G., KRAUS, ALLISON L · 2021 to 2025
$3.8M
Chemical-Genetic Approaches to Define Lrrk2 Kinase Function in Parkinson DiseaseK08NS090633 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HINIKER, ANNIE E · 2014 to 2018
$1.1M
Pathological and cognitive correlations of real time quaking induced conversion in LBD and ADK23NS120038 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI COUGHLIN, DAVID G · 2021 to 2025
$828k
NIA NIH HHS P30 AG062429NIA NIH HHS R01 AG067607NINDS NIH HHS K08 NS090633NINDS NIH HHS K23 NS120038NINDS NIH HHS L30 NS123995NINDS NIH HHS R01 NS118760
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer DiseaseSupranuclear Palsy, ProgressiveCarbolinesHumansProtein Isoformstau ProteinsCarbolinesProtein Isoformstau Proteins

Identifiers

PMID35980456
PMCPMC9467964
OpenAlexW4292242351

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.