Evidence map›Paper›PMID 35980196›Full record

ArticleMicrobiology spectrum2022

RNA-Dependent RNA Polymerase of the Second Human Pegivirus Exhibits a High-Fidelity Feature.

Shuyi Chen, Jiqin Wu, Xiaofeng Yang, Qiuli Sun, Su Liu, Farooq Rashid, Emmanuel Enoch Dzakah, Haiying Wang, Jufang Wang, Peng Gong and 1 more

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. The Blood Virome: A new frontier in biomedical science.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Shuyi Chen *Department of Epidemiology, School of Public Health, Southern Medical Universitygrid.284723.8, Guangzhou, China.
Jiqin Wu *Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virologygrid.439104.b, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.ORCID 0000-0002-6775-7724
Xiaofeng YangSchool of Biology and Biological Engineering, South China University of Technologygrid.79703.3a, Guangzhou, China.ORCID 0000-0002-0828-0807
Qiuli SunSchool of Biology and Biological Engineering, South China University of Technologygrid.79703.3a, Guangzhou, China.
Su LiuSchool of Biology and Biological Engineering, South China University of Technologygrid.79703.3a, Guangzhou, China.
Farooq RashidDepartment of Epidemiology, School of Public Health, Southern Medical Universitygrid.284723.8, Guangzhou, China.
Emmanuel Enoch DzakahDepartment of Molecular Biology & Biotechnology, School of Biological Sciences, College of Agriculture and Natural Sciences, University of Cape Coastgrid.413081.f, Cape Coast, Ghana.
Haiying WangDepartment of Epidemiology, School of Public Health, Southern Medical Universitygrid.284723.8, Guangzhou, China.
Jufang WangSchool of Biology and Biological Engineering, South China University of Technologygrid.79703.3a, Guangzhou, China.ORCID 0000-0002-9908-1001
Peng GongKey Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virologygrid.439104.b, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.ORCID 0000-0002-8264-7523
Shixing TangDepartment of Epidemiology, School of Public Health, Southern Medical Universitygrid.284723.8, Guangzhou, China.ORCID 0000-0001-9637-1874
South China University of Technology · CNSouthern Medical University · CNChinese Academy of Sciences · CNUniversity of Cape Coast · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The virus-encoded RNA-dependent RNA polymerase (RdRp) is responsible for viral replication, and its fidelity is closely related to viral diversity, pathogenesis, virulence, and fitness. Hepatitis C virus (HCV) and the second human pegivirus (HPgV-2) belong to the family

Indexed as

CoinfectionFlaviviridae InfectionsHepatitis CHepatitis C, ChronicRNA VirusesAntiviral AgentsHepacivirusHumansNucleosidesPegivirusPhylogenyRNA-Dependent RNA PolymeraseRNA, ViralSofosbuvirAntiviral AgentsNucleosidesRNA-Dependent RNA PolymeraseRNA, ViralSofosbuvirfidelityRNA-dependent RNA polymerasesecond human pegivirusviral diversity

Identifiers

PMID35980196
PMCPMC9603181
OpenAlexW4292202307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.