Evidence map›Paper›PMID 35980188›Full record

ArticleMicrobiology spectrum2022

Detecting KPC-2 and NDM-1 Coexpression in Klebsiella pneumoniae Complex from Human and Animal Hosts in South America.

Felipe Vásquez-Ponce, Karine Dantas, Johana Becerra, Gregory Melocco, Fernanda Esposito, Brenda Cardoso, Larissa Rodrigues, Keila Lima, Aline V de Lima, Fábio P Sellera and 9 more

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  13. Characterization ofAntibiotics (Basel, Switzerland) · 2023
    Article
  14. Characterisation of a Novel Hybrid IncFIIInfection and drug resistance · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 2 countries.

Felipe Vásquez-Ponce *Department of Microbiology, Institute of Biomedical Sciences, Universidade de São Paulo, São Paulo, Brazil.ORCID 0000-0002-9447-8325
Karine Dantas *Department of Microbiology, Institute of Biomedical Sciences, Universidade de São Paulo, São Paulo, Brazil.
Johana BecerraDepartment of Microbiology, Institute of Biomedical Sciences, Universidade de São Paulo, São Paulo, Brazil.
Gregory MeloccoDepartment of Clinical Analysis, School of Pharmacy, Universidade de São Paulo, São Paulo, Brazil.
Fernanda EspositoDepartment of Clinical Analysis, School of Pharmacy, Universidade de São Paulo, São Paulo, Brazil.
Brenda CardosoDepartment of Microbiology, Institute of Biomedical Sciences, Universidade de São Paulo, São Paulo, Brazil.
Larissa RodriguesDepartment of Microbiology, Institute of Biomedical Sciences, Universidade de São Paulo, São Paulo, Brazil.
Keila LimaDepartment of Clinical Analysis, School of Pharmacy, Universidade de São Paulo, São Paulo, Brazil.
Aline V de LimaDepartment of Clinical Analysis, School of Pharmacy, Universidade de São Paulo, São Paulo, Brazil.
Fábio P SelleraDepartment of Internal Medicine, School of Veterinary Medicine and Animal Science, Universidade de São Paulo, São Paulo, Brazil.
Renata MattosLaborclin, Pinhais, Brazil.
Lucas TrevisoliLaborclin, Pinhais, Brazil.
Marco A VianelloNatal Garrison Hospital, Brazilian Army, Natal, Brazil.
Thais SinceroDepartment of Clinical Analysis, Health Sciences Center, Federal University of Santa Catarina, Florianópolis, Brazil.
Jose Di ConzaFacultad de Farmacia y Bioquímica, Instituto de Investigaciones en Bacteriologia y Virología Molecular, Universidad de Buenos Aires, Buenos Aires, Argentina.
Eliana VesperoDepartment of Pathology, Clinical and Toxicological Analysis, Health Sciences Center, University Hospital of Londrina, Paraná, Brazil.
Gabriel GutkindFacultad de Farmacia y Bioquímica, Instituto de Investigaciones en Bacteriologia y Virología Molecular, Universidad de Buenos Aires, Buenos Aires, Argentina.ORCID 0000-0003-1999-9785
Jorge SampaioDepartment of Clinical Analysis, School of Pharmacy, Universidade de São Paulo, São Paulo, Brazil.
Nilton LincopanDepartment of Microbiology, Institute of Biomedical Sciences, Universidade de São Paulo, São Paulo, Brazil.ORCID 0000-0003-0161-5800
Universidade de São Paulo · BRUniversidad de Buenos Aires · ARUniversidade Estadual de Londrina · BRUniversidade Federal de Santa Catarina · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reports of Gram-negative bacteria harboring multiple carbapenemase genes have increased in South America, leading to an urgent need for appropriate microbiological diagnosis. We evaluated phenotypic methods for detecting Klebsiella pneumoniae carbapenemase 2 (KPC-2) and New Delhi metallo-β-lactamase-1 (NDM-1) coexpression in members of the K. pneumoniae complex (i.e., K. pneumoniae, K. quasipneumoniae, and K. variicola) isolated from human and animal hosts, based on inhibition of ceftazidime-avibactam (CZA) and aztreonam (ATM) by dipicolinic acid (DPA), EDTA, or avibactam (AVI). While the presence of

Indexed as

CeftazidimeKlebsiella InfectionsAnimalsAnti-Bacterial AgentsAzabicyclo CompoundsAztreonamBacterial Proteinsbeta-LactamasesEdetic AcidHumansKlebsiellaKlebsiella pneumoniaeMicrobial Sensitivity TestsAnti-Bacterial AgentsavibactamAzabicyclo CompoundsAztreonamBacterial Proteinsbeta-lactamase NDM-1beta-LactamasesCeftazidimeEdetic Acidavibactamaztreonamcarbapenemasescombined disk testcoproductiondisk approximation testimmunochromatographyK. quasipneumoniaeK. variicola

Identifiers

PMID35980188
PMCPMC9604071
OpenAlexW4292202380

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.