Evidence map›Paper›PMID 35980027›Full record

ArticleeLife2022

Audiovisual task switching rapidly modulates sound encoding in mouse auditory cortex.

Ryan J Morrill, James Bigelow, Jefferson DeKloe, Andrea R Hasenstaub

Abstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Timing and Convergence of Ensemble Activity Govern Auditory Thalamocortical Transmission.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ryan J MorrillColeman Memorial Laboratory, University of California, San Francisco, San Francisco, United States.ORCID 0000-0002-8592-4549
James BigelowColeman Memorial Laboratory, University of California, San Francisco, San Francisco, United States.
Jefferson DeKloeColeman Memorial Laboratory, University of California, San Francisco, San Francisco, United States.
Andrea R HasenstaubColeman Memorial Laboratory, University of California, San Francisco, San Francisco, United States.ORCID 0000-0003-3998-5073

Funding

Dynamic regulation of auditory context processing by cortical inhibitionR01DC014101 · NIDCD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HASENSTAUB, ANDREA RAYNE · 2014 to 2018
$1.9M
Cortical circuitry supporting flexible audiovisual interactions and behaviorsRF1NS116598 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HASENSTAUB, ANDREA RAYNE · 2020 to 2022
$1.8M
Cortical circuitry supporting flexible audiovisual interactions and behaviorsR01NS116598 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HASENSTAUB, ANDREA RAYNE · 2023 to 2024
$1.0M
Cortical reorganization and signal-in-noise processing following asymmetric hearing lossF32DC016846 · NIDCD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BIGELOW, JAMES · 2018 to 2021
$202k
NIDCD NIH HHS F32 DC016846NIDCD NIH HHS R01 DC014101NINDS NIH HHS R01 NS116598NINDS NIH HHS RF1 NS116598
6 · The paper itself

Abstract

In everyday behavior, sensory systems are in constant competition for attentional resources, but the cellular and circuit-level mechanisms of modality-selective attention remain largely uninvestigated. We conducted translaminar recordings in mouse auditory cortex (AC) during an audiovisual (AV) attention shifting task. Attending to sound elements in an AV stream reduced both pre-stimulus and stimulus-evoked spiking activity, primarily in deep-layer neurons and neurons without spectrotemporal tuning. Despite reduced spiking, stimulus decoder accuracy was preserved, suggesting improved sound encoding efficiency. Similarly, task-irrelevant mapping stimuli during inter-trial intervals evoked fewer spikes without impairing stimulus encoding, indicating that attentional modulation generalized beyond training stimuli. Importantly, spiking reductions predicted trial-to-trial behavioral accuracy during auditory attention, but not visual attention. Together, these findings suggest auditory attention facilitates sound discrimination by filtering sound-irrelevant background activity in AC, and that the deepest cortical layers serve as a hub for integrating extramodal contextual information.

Indexed as

Auditory CortexAcoustic StimulationAnimalsAuditory PerceptionMicePhotic StimulationSoundVisual Perceptionattentionbehaviorcortical layerscross-modalextracellular physiologymousemultisensoryneuroscience

Identifiers

PMID35980027
PMCPMC9427107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.