Evidence map›Paper›PMID 35979966›Full record

ArticleAmerican journal of physiology. Renal physiology2022

Aristolochic acid-induced nephropathy is attenuated in mice lacking the neutral amino acid transporter B

Aleix Navarro Garrido, Young Chul Kim, Yuji Oe, Haiyan Zhang, Maria Crespo-Masip, Helen A Goodluck, Sadhana Kanoo, Paul W Sanders, Stefan Bröer, Volker Vallon

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 34 citations in OpenAlex.

  1. Glucagon receptor agonist aggravates a murine model of Balkan nephropathy.American journal of physiology. Renal physiology · 2026
    Article
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  3. Review
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  5. Review
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  7. Beyond SGLT2: proximal tubule transporters as potential drug targets for chronic kidney disease.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Review
  8. Western diet exacerbates a murine model of Balkan nephropathy.American journal of physiology. Renal physiology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Amino acid metabolism in kidney health and disease.Nature reviews. Nephrology · 2024
    Review
  14. Review
  15. How can inhibition of glucose and sodium transport in the early proximal tubule protect the cardiorenal system?Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Review
  16. Article
  17. Article
  18. Branched-Chain Amino Acid Accumulation Fuels the Senescence-Associated Secretory Phenotype.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Aleix Navarro GarridoDepartment of Medicine, University of California-San Diego, La Jolla, California.
Young Chul KimDepartment of Medicine, University of California-San Diego, La Jolla, California.
Yuji OeDepartment of Medicine, University of California-San Diego, La Jolla, California.
Haiyan ZhangDepartment of Pathology, University of California-San Diego, San Diego, California.
Maria Crespo-MasipDepartment of Medicine, University of California-San Diego, La Jolla, California.
Helen A GoodluckDepartment of Medicine, University of California-San Diego, La Jolla, California.
Sadhana KanooDepartment of Medicine, University of California-San Diego, La Jolla, California.
Paul W SandersDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0002-2915-5714
Stefan BröerResearch School of Biology, Australian National University, Canberra, ACT, Australia.ORCID 0000-0002-8040-1634
Volker VallonDepartment of Medicine, University of California-San Diego, La Jolla, California.ORCID 0000-0002-9211-2063
University of California San Diego · USAustralian National University · AUUniversity of Alabama at Birmingham · US

Funding

UAB-UCSD O'Brien Core Center for Acute Kidney Injury ResearchP30DK079337 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AGARWAL, ANUPAM · 2008 to 2022
$18.3M
UAB-UCSD O'Brien Center for Acute Kidney Injury ResearchU54DK137307 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ANUPAM AGARWAL · 2023 to 2026
$4.4M
Glomerular and Tubular Function in the Diabetic KidneyR01DK112042 · NIDDK · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI SCOTT Culver THOMSON, Volker Vallon · 2017 to 2026
$4.1M
The Contribution of Kidney Disease to Age-Associated Cognitive DeclineRF1AG061296 · NIA · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI MAHER, PAMELA ANNE · 2019 to 2019
$3.2M
NIA NIH HHS RF1 AG061296NIDDK NIH HHS P30 DK079337NIDDK NIH HHS R01 DK112042NIDDK NIH HHS U54 DK137307
6 · The paper itself

Abstract

B

Indexed as

Amino Acids, NeutralAmino Acid Transport Systems, NeutralAristolochic AcidsKidney DiseasesAlbuminsAnimalsCreatinineFemaleFibrosisGlucoseMiceRNA, MessengerAlbuminsAmino Acids, NeutralAmino Acid Transport Systems, Neutralaristolochic acid IAristolochic AcidsCreatinineGlucoseRNA, MessengerSLC6A19 protein, mouseamino acid transportaristolochic acidB0AT1nephropathyproximal tubule

Identifiers

PMID35979966
PMCPMC9484999
OpenAlexW4292491883

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.