Evidence map›Paper›PMID 35979964›Full record

ArticleOrthopaedic surgery2022

Automated Magnetic Resonance Image Segmentation of Spinal Structures at the L4-5 Level with Deep Learning: 3D Reconstruction of Lumbar Intervertebral Foramen.

Tao Chen, Zhi-Hai Su, Zheng Liu, Min Wang, Zhi-Fei Cui, Lei Zhao, Lian-Jun Yang, Wei-Cong Zhang, Xiang Liu, Jin Liu and 5 more

Abstract read
In one paragraph

Article in Orthopaedic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Artificial Intelligence in Planning for Spine Surgery.Current reviews in musculoskeletal medicine · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. MRI evaluation of lumbar foraminal stenosis: correlation between a new quantitative evaluation and the qualitative Lee's classification.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tao ChenDepartment of Spinal Surgery, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Zhi-Hai SuDepartment of Spinal Surgery, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Zheng LiuDepartment of Spinal Surgery, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Min WangDepartment of Spinal Surgery, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Zhi-Fei CuiDepartment of Spinal Surgery, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Lei ZhaoSchool of Biomedical Engineering, Southern Medical University, Guangdong Provincial Key Laboratory of Medical Image Processing, Guangzhou, China.
Lian-Jun YangDepartment of Spinal Surgery, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Wei-Cong ZhangDepartment of Spinal Surgery, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Xiang LiuDepartment of Spinal Surgery, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Jin LiuDepartment of Radiology, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Shu-Yuan TanSchool of Biomedical Engineering, Sun Yat-sen University, Shenzhen, China.
Shao-Lin LiDepartment of Radiology, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Qian-Jin FengSchool of Biomedical Engineering, Southern Medical University, Guangdong Provincial Key Laboratory of Medical Image Processing, Guangzhou, China.
Shu-Mao PangSchool of Biomedical Engineering, Guangzhou Medical University, Guangzhou, China.
Hai LuDepartment of Spinal Surgery, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.ORCID https://orcid.org/0000-0002-4212-3282

Funding

China Postdoctoral Science Foundation 2019M663269Guangdong Province Basic and Applied Basic Research Fund 2019A1515110393National Natural Science Foundation of China 12126603National Natural Science Foundation of China 62001207Zhuhai City Innovation and Innovation Team Project ZH0406190031PWCZhuhai Industry-University-Research Project ZH22017002210017PWC
6 · The paper itself

Abstract

objective3D reconstruction of lumbar intervertebral foramen (LIVF) has been beneficial in evaluating surgical trajectory. Still, the current methods of reconstructing the 3D LIVF model are mainly based on manual segmentation, which is laborious and time-consuming. This study aims to explore the feasibility of automatically segmenting lumbar spinal structures and increasing the speed and accuracy of 3D lumbar intervertebral foramen (LIVF) reconstruction on magnetic resonance image (MRI) at the L4-5 level.

methodsA total of 100 participants (mean age: 42.2 ± 14.0 years; 52 males and 48 females; mean body mass index, 22.7 ± 3.2 kg/m

resultsThe automatic segmentation performance of all spinal structures (VBS and IVD) was found to be 0.918 (healthy levels: 0.922; unhealthy levels: 0.916) for the mean DSC, 0.922 (healthy levels: 0.927; unhealthy levels: 0.920) for the mean precision, and 0.917 (healthy levels: 0.918; unhealthy levels: 0.917) for the mean recall in the test dataset. It took approximately 2.5 s to achieve each automated segmentation, far less than the 240 min for manual segmentation. Furthermore, no significant differences were observed in the foraminal area, height and width of the 3D LIVF models between manual and automatic segmentation images (P > 0.05).

conclusionA method of automated MRI segmentation based on deep learning algorithms was capable of rapidly generating accurate segmentation of spinal structures and can be used to construct 3D LIVF models from MRI at the L4-5 level.

Indexed as

Deep LearningImaging, Three-DimensionalAdultFemaleHumansLumbar VertebraeMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesReproducibility of Results3D reconstructionAutomated magnetic resonance image segmentationDeep learningLumbar intervertebral foramen

Identifiers

PMID35979964
PMCPMC9483078

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.