Evidence map›Paper›PMID 35979834›Full record

ArticleAIDS (London, England)2022

Mitoquinone mesylate attenuates brain inflammation in humanized mouse model of chronic HIV infection.

Sandro Satta, Cristelle Hugo, Madhav Sharma, Valerie Rezek, Athanassios Kossyvakis, Shubhendu Sen Roy, Scott Kitchen, Theodoros Kelesidis

Open access · greenAbstract read
In one paragraph

Article in AIDS (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sandro SattaDivision of Infectious Diseases.
Cristelle HugoDivision of Infectious Diseases.
Madhav SharmaDivision of Infectious Diseases.
Valerie RezekDivision of Hematology and Oncology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Athanassios KossyvakisDivision of Infectious Diseases.
Shubhendu Sen RoyDivision of Infectious Diseases.
Scott KitchenDivision of Hematology and Oncology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Theodoros KelesidisDivision of Infectious Diseases.
Office of Infectious Diseases · US

Funding

Virology CoreP30AI028697 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JAMIESON-KARAVODIN, BETH DEIRDRE · 1991 to 2018
$39.9M
Viral Immunology CoreU19AI117941 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SYMONDS, GEOFFREY · 2015 to 2019
$10.6M
UCLA MSD ProgramR25GM055052 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BARBER, PAUL HENRY, HASSON, TAMA W. · 1996 to 2021
$9.2M
Targeting early instigators of vascular inflammation to prevent and/or delay vascular aging in chronic treated HIVR01AG059502 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI KELESIDIS, THEODOROS · 2018 to 2022
$2.0M
The role of CD4 in macrophage differentiation and functionR01AI078806 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KITCHEN, SCOTT G · 2009 to 2013
$1.9M
Oxidized HDL in the intersection of HIV, immune activation and atherosclerosisK08AI108272 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KELESIDIS, THEODOROS · 2013 to 2017
$915k
In vivo modelling of therapeutic strategies for prevention of HIV-related fibrosis and fatty liver disease in chronic treated HIV-1 infectionR21AI136708 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KELESIDIS, THEODOROS · 2018 to 2019
$429k
Targeting Type I Interferon Immune Activation to Control HIV Infection in vivoR21AI110306 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KITCHEN, SCOTT G · 2014 to 2015
$424k
Humanized mice as a model to study the role of oxidized lipids in HIV-related cardiovascular diseaseR21HL134444 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KELESIDIS, THEODOROS, REDDY, SRINIVASA T. · 2016 to 2017
$424k
Selective Tuning of Stem Cell Extracellular Vesicles as a Novel Therapy for Age-related TendinopathyR43AG059501 · NIA · ZEN-BIO, INC. · PI BUEHRER, BENJAMIN M, LUDLOW, JOHN WILLIAM · 2018 to 2018
$222k
Elucidating the impact of molecular signatures of immune senescence on aging in chronic treated HIVR03AG059462 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KELESIDIS, THEODOROS · 2018 to 2019
$156k
Humanized mice as a model to study novel therapies for HIV-Associated Neurocognitive Disorders (HAND) in elderly HIV-1 infected individualsR03AG056189 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KELESIDIS, THEODOROS · 2018 to 2019
$156k
NHLBI NIH HHS R21 HL134444NIAID NIH HHS K08 AI108272NIAID NIH HHS P30 AI028697NIAID NIH HHS R01 AI078806NIAID NIH HHS R21 AI110306NIAID NIH HHS R21 AI136708NIAID NIH HHS U19 AI117941NIA NIH HHS R01 AG059502NIA NIH HHS R03 AG056189NIA NIH HHS R03 AG059462NIA NIH HHS R43 AG059501NIGMS NIH HHS R25 GM055052
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EncephalitisHIV InfectionsAnimalsDisease Models, AnimalMesylatesMiceOrganophosphorus CompoundsUbiquinoneMesylatesmitoquinoneOrganophosphorus CompoundsUbiquinone

Identifiers

PMID35979834
PMCPMC10924803
OpenAlexW4292242325

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.