ArticleWorld journal of clinical cases2022
Acute methanol poisoning with bilateral diffuse cerebral hemorrhage: A case report.
Article in World journal of clinical cases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 4 citations in OpenAlex.
- Postmortem Methanol and Formic Acid Levels and Their Pathological Correlates: Diagnostic Implications from an Autopsy Study.Diagnostics (Basel, Switzerland) · 2026Article
- Occupational methanol toxicity: a case report study.Frontiers in medicine · 2025Article
- Ischemic and Hemorrhagic Brain Damage in Methanol Poisoning: A Case of Rapid Deterioration.The American journal of case reports · 2024Article
- Intracerebral hemorrhage in methanol toxicity patients during COVID-19 pandemic: case report and review of literature.Forensic toxicology · 2024Review
- Outbreak of methanol-induced optic neuropathy in early COVID-19 era; effectiveness of erythropoietin and methylprednisolone therapy.World journal of clinical cases · 2023Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute methanol poisoning (AMP) is a systemic disease that mainly affects the central nervous system and is characterized by ocular damage and metabolic acidosis. If appropriate treatments are inadequate or delayed, the mortality can exceed 40%. As the most serious complication, cerebral hemorrhage is rare with reported prevalence of 7%-19%. CASE SUMMARY: A 62-year-old man drank liquor mixed with 45% methanol and 35% alcohol. His vision blurred 10 h later and he fell into coma in another 9 h. Serum toxicological tests were performed immediately, and continuous renal replacement therapy (CRRT) was carried out as the lactic acid exceeded 15 mmol/L and blood pH was 6.78. In addition, the toxicological report revealed 1300.5 μg/mL of methanol in serum and 1500.2 μg/mL in urine. After 59 h of CRRT, the methanol level decreased to 126.0 μg/mL in serum and 151.0 μg/mL in urine. However, the patient was still unconscious and his pupillary light reflex was slow. Computed tomography showed hemorrhage in the left putamen. After 16 d of life support treatment, putamen hemorrhage developed into diffuse symmetric intracerebral hemorrhage. In the end, his family gave up and the patient was discharged, and died in a local hospital.
conclusionCerebral hemorrhage requires constant vigilance during the full course of treatment for severe cases of AMP.
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