ArticleWorld journal of clinical cases2022
Preliminary evidence in treatment of eosinophilic gastroenteritis in children: A case series.
Article in World journal of clinical cases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 4 citations in OpenAlex.
- Is Eosinophilic Colitis a Forerunner of Inflammatory Bowel Disease?Current gastroenterology reports · 2025Review
- Eosinophilic gastrointestinal disorders: a narrative review on clinical perspectives and research gaps in the Asian context.Translational gastroenterology and hepatology · 2024Review
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEosinophilic gastroenteritis is a rare inflammatory disorder in children. However, there is still no standard guideline in the treatment of pediatric eosinophilic gastroenteritis.
aimTo report our experience with the diagnosis and treatment of children with eosinophilic gastroenteritis.
methodsFrom January 2017 to December 2019, a total of 22 children were diagnosed with eosinophilic gastroenteritis.
resultsEndoscopic examination showed eosinophil infiltration in the duodenum [mean number of eosinophils/high-power field (HPF) = 53.1 ± 81.5], stomach (mean number of eosinophils/HPF = 36.8 ± 50.5), and terminal ileum (mean number of eosinophils/HPF = 49.0 ± 24.0). All 18 children with low eosinophil infiltration (< 14%) responded well to the initial drug treatment without relapse, while two of four children with high eosinophil infiltration (> 14%) relapsed after initial methylprednisolone/montelukast treatment. In addition, children with high eosinophil infiltration (> 14%) showed symptomatic relief and histological remission without further relapse after receiving budesonide/methylprednisolone as initial or relapse treatment.
conclusionMethylprednisolone/montelukast is still the best treatment for children with low eosinophil infiltration (< 14%). Budesonide can be considered as the initial or relapse treatment for children with high eosinophil infiltration (> 14%).
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