Evidence map›Paper›PMID 35979233›Full record

ArticleFrontiers in pharmacology2022

Case Report: Good cardiac tolerance to Toripalimab in a CVD patient with oral melanoma.

Wei Pan, Li Yin, Yadi Guo, Dachao Pan, Hui Huang

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Wei PanCardiovascular Department, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen, China.
Li YinCardiovascular Department, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen, China.
Yadi GuoCardiovascular Department, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen, China.
Dachao PanOncology Department, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen, China.
Hui HuangCardiovascular Department, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen, China.
Eighth Affiliated Hospital of Sun Yat-sen UniversitySun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary oral melanoma is extremely rare, and the prognosis is very poor. With the development of immunotherapy, melanoma's treatment landscape changed dramatically. Toripalimab, a recombinant programmed death receptor 1 (PD-1) monoclonal antibody, has been approved as second-line therapy for metastatic melanoma. However, the cardiac toxicity of Toripalimab is seldom reported. This article describes the application of Toripalimab on a patient who suffered from primary oral melanoma accompanied with arrhythmic mitral valve prolapse (AMVP).

Indexed as

arrhythmic mitral valve prolapsecancer treatmentcardiovascular toxicityimmunotherapymelanoma

Identifiers

PMID35979233
PMCPMC9376878
OpenAlexW4289201895

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.