Evidence map›Paper›PMID 35979061›Full record

ArticleFrontiers in neurology2022

Spinal Obstruction-Related vs. Craniocervical Junction-Related Syringomyelia: A Comparative Study.

Chenghua Yuan, Jian Guan, Yueqi Du, Zeyu Fang, Xinyu Wang, Qingyu Yao, Can Zhang, Shanhang Jia, Zhenlei Liu, Kai Wang and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. A novel Minimally-Invasive technique for Non-Traumatic postoperative adhesive Syringomyelia.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Chenghua YuanDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Jian GuanDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Yueqi DuDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Zeyu FangDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Xinyu WangDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Qingyu YaoDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Can ZhangDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Shanhang JiaDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Zhenlei LiuDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Kai WangDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Wanru DuanDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Xingwen WangDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Zuowei WangDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Hao WuDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Zan ChenDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Fengzeng JianDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: No prior reports have focused on spinal cord injury (SCI) characteristics or inflammation after destruction of the blood-spinal cord barrier by syringomyelia. This study aimed to determine the differences in syringomyelia-related central SCI between craniocervical junction (CCJ) syringomyelia and post-traumatic syringomyelia (PTS) before and after decompression. Methods: In all, 106 CCJ, 26 CCJ revision and 15 PTS patients (mean history of symptoms, 71.5 ± 94.3, 88.9 ± 85.5, and 32.3 ± 48.9 months) between 2015 and 2019 were included. The symptom course was analyzed with the American Spinal Injury Association ASIA and Klekamp-Samii scoring systems, and neurological changes were analyzed by the Kaplan-Meier statistics. The mean follow-up was 20.7 ± 6.2, 21.7 ± 8.8, and 34.8 ± 19.4 months. Results: The interval after injury was longer in the PTS group, but the natural history of syringomyelia was shorter ( Conclusion: PTS tends to progress faster than CCJ-related syringomyelia. Except for the RBC count, PBIMs showed no value in distinguishing the two forms of syringomyelia. The predictive value of the neutrophil-to-lymphocyte ratio for syringomyelia-related inflammation was negative except in the acute phase.

Indexed as

biomarkerCSFdecompressionspinal cord injurysyringomyelia

Identifiers

PMID35979061
PMCPMC9376629
OpenAlexW4289170227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.