Evidence map›Paper›PMID 35978877›Full record

ReviewWorld journal of gastroenterology2022

Long noncoding RNAs in hepatitis B virus replication and oncogenesis.

Hui-Chun Li, Chee-Hing Yang, Shih-Yen Lo

Open access · greenAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hui-Chun LiDepartment of Biochemistry, Tzu Chi University, Hualien 97004, Taiwan.
Chee-Hing YangDepartment of Laboratory Medicine and Biotechnology, Tzu Chi University, Hualien 97004, Taiwan.
Shih-Yen LoDepartment of Laboratory Medicine and Biotechnology, Tzu Chi University, Hualien 97004, Taiwan.
Tzu Chi University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several diverse long noncoding RNAs (lncRNAs) have been identified to be involved in hepatitis B virus (HBV) replication and oncogenesis, especially those dysregulated in HBV-related hepatocellular carcinoma (HCC). Most of these dysregulated lncRNAs are modulated by the HBV X protein. The regulatory mechanisms of some lncRNAs in HBV replication and oncogenesis have been characterized. Genetic polymorphisms of several lncRNAs affecting HBV replication or oncogenesis have also been studied. The prognosis of HCC remains poor. It is important to identify novel tumor markers for early diagnosis and find more therapeutic targets for effective treatments of HCC. Some dysregulated lncRNAs in HBV-related HCC may become biomarkers for early diagnosis and/or the therapeutic targets of HCC. This mini-review summarizes these findings briefly, focusing on recent developments.

Indexed as

Carcinoma, HepatocellularHepatitis BLiver NeoplasmsRNA, Long NoncodingCarcinogenesisCell Transformation, NeoplasticGene Expression Regulation, NeoplasticHepatitis B virusHumansVirus ReplicationRNA, Long NoncodingBiomarkerHepatitis B virusHepatitis B virus X proteinHepatocellular carcinomaLong noncoding RNAs

Identifiers

PMID35978877
PMCPMC9280728
OpenAlexW4283764052

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.