Evidence map›Paper›PMID 35978719›Full record

ArticleRespirology case reports2022

GM-CSF antibodies in artificial stone associated silicoproteinosis: A case report and literature review.

Shana N S Khan, Robert G Stirling, Catriona A Mclean, Prudence A Russell, Ryan F Hoy

Open access · goldAbstract readCase Reports
In one paragraph

Article in Respirology case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. A Comprehensive Outlook on Pulmonary Alveolar Proteinosis-A Review.International journal of molecular sciences · 2024
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shana N S KhanDepartment of Respiratory Medicine Alfred Health Melbourne Victoria Australia.ORCID https://orcid.org/0000-0002-3973-6168
Robert G StirlingDepartment of Respiratory Medicine Alfred Health Melbourne Victoria Australia.ORCID https://orcid.org/0000-0001-9877-5450
Catriona A McleanDepartment of Medicine Monash University Melbourne Victoria Australia.ORCID https://orcid.org/0000-0002-0302-5727
Prudence A RussellTissuPath Melbourne Victoria Australia.ORCID https://orcid.org/0000-0001-5703-9414
Ryan F HoyDepartment of Respiratory Medicine Alfred Health Melbourne Victoria Australia.ORCID https://orcid.org/0000-0001-9150-9440
Alfred Health · AUTissuPath · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary alveolar proteinosis (PAP) is a rare lung disease where there is accumulation of surfactant in the alveoli. It can be classified based on the underlying aetiology into three categories: primary, secondary and congenital. Autoantibodies to granulocyte-macrophage colony-stimulating factor (GM-CSF-Ab) are a key diagnostic feature of autoimmune PAP. High intensity occupational exposure and inhalation of toxic particles such as silica can cause a form of secondary PAP called acute silicoproteinosis. We describe a 26-year-old stone benchtop fabricator with silicoproteinosis following daily exposure to high levels of silica who had elevated serum GM-CSF-Ab. We discuss the role of GM-CSF-Ab in cases of PAP with occupational inhalational exposure and the challenges in its interpretation.

Indexed as

occupational diseasepulmonary alveolar proteinosissilicasilicoproteinosisstone benchtop

Identifiers

PMID35978719
PMCPMC9366405
OpenAlexW4292729105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.