Evidence map›Paper›PMID 35978716›Full record

ArticleWorld journal of gastrointestinal endoscopy2022

Role of endoscopic ultrasound and cyst fluid tumor markers in diagnosis of pancreatic cystic lesions.

Hussein Hassan Okasha, Abeer Abdellatef, Shaimaa Elkholy, Mohamad-Sherif Mogawer, Ayman Yosry, Magdy Elserafy, Eman Medhat, Hanaa Khalaf, Magdy Fouad, Tamer Elbaz and 20 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastrointestinal endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. In-Depth Analysis of theInternational journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 11 institutions in 1 country.

Hussein Hassan OkashaDepartment of Internal Medicine and Hepatogastroenterology, Kasr Al-Aini Hospitals, Cairo University, Kasr Al-Aini Hospitals, Cairo University, Cairo 11451, Egypt.
Abeer AbdellatefDepartment of Internal Medicine and Hepatogastroenterology, Kasr Al-Aini Hospitals, Cairo University, Kasr Al-Aini Hospitals, Cairo University, Cairo 11451, Egypt. beero4a@yahoo.com.
Shaimaa ElkholyDepartment of Internal Medicine and Hepatogastroenterology, Kasr Al-Aini Hospitals, Cairo University, Kasr Al-Aini Hospitals, Cairo University, Cairo 11451, Egypt.
Mohamad-Sherif MogawerDepartment of Internal Medicine and Hepatogastroenterology, Kasr Al-Aini Hospitals, Cairo University, Kasr Al-Aini Hospitals, Cairo University, Cairo 11451, Egypt.
Ayman YosryDepartment of Endemic Diseases, Cairo University, Cairo 11451, Egypt.
Magdy ElserafyDepartment of Endemic Diseases, Cairo University, Cairo 11451, Egypt.
Eman MedhatDepartment of Endemic Diseases, Cairo University, Cairo 11451, Egypt.
Hanaa KhalafDepartment of Tropical Medicine and Gastroenterology, Minia University, Minia 61511, Egypt.
Magdy FouadDepartment of Tropical Medicine and Gastroenterology, Minia University, Minia 61511, Egypt.
Tamer ElbazDepartment of Endemic Diseases, Cairo University, Cairo 11451, Egypt.
Ahmed RamadanDepartment of Endemic Diseases, Cairo University, Cairo 11451, Egypt.
Mervat E BehiryDepartment of Internal Medicine, Kasr Al-Aini Hospitals, Cairo University, Cairo 11562, Egypt.
Kerolis Y WilliamDepartment of Internal Medicine and Hepatogastroenterology, Kasr Al-Aini Hospitals, Cairo University, Kasr Al-Aini Hospitals, Cairo University, Cairo 11451, Egypt.
Ghada HabibDepartment of Endemic Diseases, Cairo University, Cairo 11451, Egypt.
Mona KaddahDepartment of Endemic Diseases, Cairo University, Cairo 11451, Egypt.
Haitham Abdel-HamidDepartment of Tropical Medicine and Gastroenterology, Minia University, Minia 61511, Egypt.
Amr Abou-ElmagdDepartment of Gastroenterology, Armed forces College of Medicine, Cairo 11451, Egypt.
Ahmed GalalEndoscopy and Internal Medicine Consultant at Dr/Ahmed Galal Endoscopy Center, Alexandria 35516, Egypt.
Wael A AbbasDepartment of Internal Medicine, Faculty of Medicine, Assuit University, Assuit 71111, Egypt.
Ahmed Youssef AltonbaryDepartment of Gastroenterology and Hepatology, Mansoura University, Mansoura 35511, Egypt.
Mahmoud El-AnsaryDepartment of Gastroenterology and Hepatology, Theodor Bilharz Research Institute, Cairo 11451, Egypt.
Aml E AbdouDepartment of Microbiology and Immunology, Faculty of Medicine for girls Al-Azhar University, Cairo 11451, Egypt.
Hani HaggagDepartment of Internal Medicine and Hepatogastroenterology, Kasr Al-Aini Hospitals, Cairo University, Kasr Al-Aini Hospitals, Cairo University, Cairo 11451, Egypt.
Tarek Ali AbdellahDepartment of Internal Medicine, Faculty of Medicine, Ain shams University, Cairo 11451, Egypt.
Mohamed A ElfekiDepartment of Internal Medicine, Bani-suef University, Bani-suef, Bani-suef 62511, Egypt.
Heba Ahmed FaheemDepartment of Internal Medicine, Faculty of Medicine, Ain shams University, Cairo 11451, Egypt.
Hani M KhattabDepartment of Pathology, Faculty of Medicine, Cairo University, Cairo 11451, Egypt.
Mervat El-AnsaryDepartment of Clinical Pathology, Faculty of Medicine, Cairo University, Cairo 11451, Egypt.
Safia BeshirDepartment of Environmental Medicine & Clinical Pathology, National Research Centre, Cairo 11451, Egypt.
Mohamed El-NadyDepartment of Internal Medicine and Hepatogastroenterology, Kasr Al-Aini Hospitals, Cairo University, Kasr Al-Aini Hospitals, Cairo University, Cairo 11451, Egypt.
Cairo University · EGCairo University hospitals · EGMinia University · EGAin Shams University · EGAl-Azhar University · EGAlexandria University · EGArmed Forces College of Medicine · EGAssiut University · EGBeni-Suef University · EGMansoura University · EGNational Research Centre · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPancreatic cystic lesions (PCLs) are common in clinical practice. The accurate classification and diagnosis of these lesions are crucial to avoid unnecessary treatment of benign lesions and missed opportunities for early treatment of potentially malignant lesions.

aimTo evaluate the role of cyst fluid analysis of different tumor markers such as cancer antigens [

methodsThis study included 76 patients diagnosed with PCLs using different imaging modalities. All patients underwent endoscopic ultrasound (EUS) and EUS-fine needle aspiration (EUS-FNA) for characterization and sampling of different PCLs.

resultsThe mean age of studied patients was 47.4 ± 11.4 years, with a slight female predominance (59.2%). Mucin stain showed high statistical significance in predicting malignancy with a sensitivity of 87.1% and specificity of 95.56%. It also showed a positive predictive value and negative predictive value of 93.1% and 91.49%, respectively (

conclusionEUS examination of cyst morphology with cytopathological analysis and cyst fluid analysis could improve the differentiation between malignant and benign pancreatic cysts. Also, CEA, glucose, and SPINK1 could be used as promising markers to predict malignant pancreatic cysts.

Indexed as

AmylaseIntraductal papillary mucinous neoplasmMucinous cystic neoplasmMucin stainPancreatic cystic neoplasm

Identifiers

PMID35978716
PMCPMC9265252
OpenAlexW4281999716

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.