Evidence map›Paper›PMID 35978666›Full record

ArticleWorld journal of hepatology2022

Gut dysbiosis and body composition in cirrhosis.

Roman Maslennikov, Vladimir Ivashkin, Aliya Alieva, Elena Poluektova, Anna Kudryavtseva, George Krasnov, Maria Zharkova, Yuri Zharikov

Open access · diamondAbstract read
In one paragraph

Article in World journal of hepatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Decreased Abundance of GenusGastro hep advances · 2024
    Article
  8. Frontiers in nutrition · 2024
    Article
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Roman MaslennikovDepartment of Internal Medicine, Gastroenterology and Hepatology, Sechenov University, Moscow 119435, Russia.
Vladimir IvashkinDepartment of Internal Medicine, Gastroenterology and Hepatology, Sechenov University, Moscow 119435, Russia.
Aliya AlievaDepartment of Internal Medicine, Gastroenterology and Hepatology, Sechenov University, Moscow 119435, Russia.
Elena PoluektovaDepartment of Internal Medicine, Gastroenterology and Hepatology, Sechenov University, Moscow 119435, Russia.
Anna KudryavtsevaScientific Community for Human Microbiome Research, Moscow 119435, Russia.
George KrasnovCenter for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.
Maria ZharkovaDepartment of Internal Medicine, Gastroenterology and Hepatology, Sechenov University, Moscow 119435, Russia.
Yuri ZharikovDepartment of Anatomy, Sechenov University, Moscow 119435, Russia.
Sechenov University · RUEngelhardt Institute of Molecular Biology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGut dysbiosis and changes in body composition (

aimTo study the relationship between the gut microbiota and body composition in cirrhosis.

methodsThis observational study included 46 patients with cirrhosis. Stool microbiome was assessed using 16S rRNA gene sequencing. Multifrequency bioelectrical impedance analysis was performed to assess body composition in these patients.

resultsAn increase in fat mass and a decrease in body cell mass were noted in 23/46 (50.0%) and 15/46 (32.6%) patients, respectively. Changes in the gut microbiome were not independently associated with the fat mass percentage in cirrhosis. The abundance of

conclusionChanges in the amount of body cell mass and extracellular fluid are associated with changes in the gut microbiome in cirrhosis patients.

Indexed as

CirrhosisDysbiosisGut-Liver axisMalnutritionMicrobiomeMicrobiotaSarcopenia

Identifiers

PMID35978666
PMCPMC9258262
OpenAlexW4283163607

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.