Evidence map›Paper›PMID 35978632›Full record

ArticleBioMed research international2022

Impact of ANN in Revealing of Viral Peptides.

M Rajkumar, Shankar Nayak Bhukya, N Ahalya, G Elumalai, K Sivanandam, Khalid M A Almutairi, Wadi B Alonazi, S R Soma, Markos Makiso Urugo

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 4 countries.

M RajkumarDepartment of Computer Science and Engineering, Rajalakshmi Engineering College, Chennai, Tamil Nadu, India.
Shankar Nayak BhukyaDepartment of Computer Science and Engineering (Data Science), CMR Technical Campus, Hyderabad, Telangana 501401, India.
N AhalyaDepartment of Biotechnology, MS Ramaiah Institute Technology, Bengaluru, Karnataka 560054, India.
G ElumalaiDepartment of Electronics and Communication Engineering, Panimalar Engineering College, Chennai, Tamil Nadu 600123, India.
K SivanandamDepartment of Electronics and Communication Engineering, M.Kumarasamy College of Engineering, Karur, Tamil Nadu 639113, India.
Khalid M A AlmutairiDepartment of Community Health Sciences, College of Applied Medical Sciences, King Saud University, P. O. Box: 10219, Riyadh 11433, Saudi Arabia.
Wadi B AlonaziHealth Administration Department, College of Business Administration, King Saud University, PO Box: 71115, Riyadh 11587, Saudi Arabia.
S R SomaDepartment of Biology, University of Tennessee Health Science Center, Memphis, USA.
Markos Makiso UrugoDepartment of Food Science and Postharvest Technology, College of Agricultural Sciences, Wachamo University, Hosaena, Ethiopia.ORCID https://orcid.org/0000-0002-6241-1417
King Saud University · SAAssam Agricultural University · INBirla Institute of Technology and Science - Hyderabad Campus · INGS Engineering (United States) · USM S Ramaiah University of Applied Sciences · INRajalakshmi Engineering CollegeSRM University · INUniversity of Tennessee Health Science Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

All organisms contain antimicrobial peptides (AMPs), which are a critical component of the innate immune system. These chemicals have the ability to suppress the growth of a variety of fungi, bacteria, and viruses. Because AMPs interact with structural components of the microbial cell membrane and have a wide range of cellular targets, bacteria are unlikely to be able to develop resistance to them in the short term. The underlying structure of AMPs is critical in determining the selectivity with which they target their respective targets. As far as we know, peptides have not been tested in a lab to see if they can fight bacteria, fungus, and viruses in real life. In this paper, we develop an artificial neural network (ANN) using a back propagation neural network (BPNN) that enables optimal classification of tendency of a peptide sequence that involves the activities of antifungal, antibacterial, or antiviral. The BPNN is trained on the datasets collected across different repositories and then the overfitting is avoided using particle swarm optimization (PSO) algorithm. Hence, at the time of testing, the BPNN clearly finds the predicted samples belonging to the same classes and this avoids the problem of finding the false positives. The simulation is conducted to test the efficacy of the model against various metrics that includes accuracy, precision, recall, and f1-measure. The effectiveness of the BPNN-PSO model in classifying instances at a faster rate than other techniques is demonstrated by its performance. The principle is straightforward, it is not difficult to programme, it converges more quickly, and it generally offers a superior solution.

Indexed as

AlgorithmsNeural Networks, ComputerAntifungal AgentsComputer SimulationPeptidesAntifungal AgentsPeptides

Identifiers

PMID35978632
PMCPMC9377878
OpenAlexW4295725729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.