Evidence map›Paper›PMID 35978467›Full record

ReviewDeutsches Arzteblatt international2022

Neurogenic Thoracic Outlet Syndrome—Presentation, Diagnosis, and Treatment.

Nora F Dengler, Maria T Pedro, Thomas Kretschmer, Christian Heinen, Steffen K Rosahl, Gregor Antoniadis

Open access · greenAbstract readReview
In one paragraph

Review in Deutsches Arzteblatt international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
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  4. Review
  5. Review
  6. Brachial Plexopathies.Current sports medicine reports · 2026
    Article
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  13. Review
  14. Don't Forget the Facet Joint Syndrome.Deutsches Arzteblatt international · 2023
    Article
  15. In Reply.Deutsches Arzteblatt international · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nora F DenglerDepartment of Neurosurgery, Charité-Universitätsmedizin Berlin; District Hospital of Günzburg, Neurosurgical Department of the University of Ulm; Department of Neurosurgery and Neurorestauration, Klinikum Klagenfurt Am Wörthersee, Klagenfurt, Austria; Peripheral Nerve Unit Nord, Christliches Krankenhaus Quakenbrück GmbH, Quakenbrück; Department of Neurosurgery, Helios Klinikum Erfurt.
Maria T Pedro
Thomas Kretschmer
Christian Heinen
Steffen K Rosahl
Gregor Antoniadis
Klinikum Klagenfurt · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThoracic outlet syndrome (TOS) refers to a group of disorders in which there is compression of and/or damage to the neurovascular structures at the thoracic outlet, i.e., at the transition from chest to neck. The incidence of neurogenic thoracic outlet syndrome (nTOS) is estimated to be 2-3 / 100 000 / year, with an estimated prevalence of 10 / 100 000. Patients present with upper extremity sensorimotor symptoms that are often related to movement. The aim of the present article is to highlight the clinical presentation patterns of nTOS and to provide an overview of its diagnosis and treatment.

methodsSelective literature search for prospective observational studies and RCTs, including systematic reviews and metaanalyses.

resultsThere is no multicenter randomized controlled trial available on the treatment of nTOS. Prospective observational studies with a hierarchical study design report a positive effect of physiotherapy in 27-59% of cases. After unsuccessful conservative treatment, up to 56-90% benefit from surgical management. Patients with nTOS are more severely affected compared with those with other forms of TOS and benefit less from transaxillary first rib resection. nTOS patients who underwent supraclavicular decompression without rib resection had excellent surgical outcomes in 27%, good outcomes in 36%, acceptable outcomes in 26%, and poor surgical outcomes in 11% of cases. There is no systematic comparison available of the types of surgical management involved. Also, there is currently no uniform classification available for all medical sub-disciplines. Therefore, interpretation, and comparability of the study results are limited.

conclusionAlthough nTOS is the most common form of TOS, studies on its treatment are currently limited in terms of numbers and quality. The type of surgical management varies according to the experience and preference of the surgeon, treating specialty, special anatomic features, and clinical symptoms.

Indexed as

Thoracic Outlet SyndromeHumansMeta-Analysis as TopicObservational Studies as TopicPhysical Therapy ModalitiesProspective StudiesRandomized Controlled Trials as TopicSystematic Reviews as TopicTreatment Outcome

Identifiers

PMID35978467
PMCPMC9975980
OpenAlexW4294993016

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.